(2S,5R,6R)-6-[2-Ethyl-2-(2-methoxycarbonyl-phenoxy)-3-methyl-butyrylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid

Base Information

• Chemical Name: (2S,5R,6R)-6-[2-Ethyl-2-(2-methoxycarbonyl-phenoxy)-3-methyl-butyrylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
• CAS No.: 125186-53-0
• Molecular Formula: C₂₃H₃₀N₂O₇S
• Molecular Weight: 478.566

Synonyms:

Chemical Property of (2S,5R,6R)-6-[2-Ethyl-2-(2-methoxycarbonyl-phenoxy)-3-methyl-butyrylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (2S,5R,6R)-6-[2-Ethyl-2-(2-methoxycarbonyl-phenoxy)-3-methyl-butyrylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid

There total 1 articles about (2S,5R,6R)-6-[2-Ethyl-2-(2-methoxycarbonyl-phenoxy)-3-methyl-butyrylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-Aminopenicillanic Acid (551-16-6) + 2-(1-Carboxy-1-ethyl-2-methyl-propoxy)-benzoic acid methyl ester → (2S,5R,6R)-6-[2-Ethyl-2-(2-methoxycarbonyl-phenoxy)-3-methyl-butyrylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (125186-53-0)

Guidance literature:

With chloroformic acid ethyl ester; sodium hydrogencarbonate; triethylamine; Yield given. Multistep reaction; 1.) a) acetone, 0 deg C, 30 min, b) RT, 2 h, 2.) 4 h;

DOI:10.1007/BF00764623

upstream raw materials:

6-Aminopenicillanic Acid

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