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4-(di(1H-indol-3-yl)Methyl)phenol

Base Information Edit
  • Chemical Name:4-(di(1H-indol-3-yl)Methyl)phenol
  • CAS No.:151358-47-3
  • Molecular Formula:C23H18N2O
  • Molecular Weight:338.409
  • Hs Code.:
  • Mol file:151358-47-3.mol
4-(di(1H-indol-3-yl)Methyl)phenol

Synonyms:1,1-bis(3'-indolyl)-1-(p-hydroxyphenyl)methane;3-[1H-indol-3-yl(4-hydroxyphenyl)methyl]-1H-indole;3,3'-((4-hydroxylphenyl)methylene)bis(1H-indole);bis-(1H-indol-3-yl)-(4-hydroxyphenyl)-methane;3,3′-(4-hydroxybenzylidene)bis(1H-indole);4-[Bis-(1H-indol-3-yl)-methyl]-phenol;3,3'-[(4-hydroxyphenyl)methylene]bis(1H-indole);

Suppliers and Price of 4-(di(1H-indol-3-yl)Methyl)phenol
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Tocris
  • DIM-C-pPhOH ≥98%(HPLC)
  • 25
  • $ 371.00
  • Tocris
  • DIM-C-pPhOH ≥98%(HPLC)
  • 5
  • $ 95.00
  • Matrix Scientific
  • 4-(Di(1H-indol-3-yl)methyl)phenol
  • 2g
  • $ 975.00
  • DC Chemicals
  • DIM-C-pPhOH(CDIM8) >98%
  • 250 mg
  • $ 700.00
  • Crysdot
  • 4-(Di(1H-indol-3-yl)methyl)phenol 97%
  • 1g
  • $ 436.00
  • Crysdot
  • 4-(Di(1H-indol-3-yl)methyl)phenol 97%
  • 5g
  • $ 1307.00
  • Chemenu
  • 4-(Di(1H-indol-3-yl)methyl)phenol 95%+
  • 5g
  • $ 1234.00
  • Chemenu
  • 4-(Di(1H-indol-3-yl)methyl)phenol 95%+
  • 1g
  • $ 411.00
  • Ambeed
  • 4-(Di(1H-indol-3-yl)methyl)phenol 97%
  • 1g
  • $ 439.00
  • Ambeed
  • 4-(Di(1H-indol-3-yl)methyl)phenol 97%
  • 250mg
  • $ 186.00
Total 17 raw suppliers
Chemical Property of 4-(di(1H-indol-3-yl)Methyl)phenol Edit
Chemical Property:
  • Melting Point:120 - 122 °C (water) 
  • Boiling Point:610.2±50.0 °C(Predicted) 
  • PKA:9.98±0.26(Predicted) 
  • PSA:51.81000 
  • Density:1.321±0.06 g/cm3(Predicted) 
  • LogP:5.53500 
  • Storage Temp.:Sealed in dry,Room Temperature 
  • Solubility.:Soluble in DMSO (35 mg/ml); ethanol (35 mg/ml) 
Purity/Quality:

99% *data from raw suppliers

DIM-C-pPhOH ≥98%(HPLC) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Description C-DIM 8 (151358-47-3) is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3).1 Induces reactive oxygen species and ER stress in pancreatic cancer cells.2 C-DIM 8 mimics the effect of Nur77 knockdown in non-small-cell lung cancer A549 and H460 cells, inhibiting cell growth and inducing apoptosis which was accompanied by decreased expression of survivin and inhibition of mTORC1 signaling.3 Inhibits the expression of β1- and β3-integrin and blocks integrin-dependent breast cancer cell migration.4 Decreases expression of the histone methyltransferase G9A (EHMT2) in a variety of cancer cell lines.5
Technology Process of 4-(di(1H-indol-3-yl)Methyl)phenol

There total 11 articles about 4-(di(1H-indol-3-yl)Methyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
In neat (no solvent); at 60 ℃; for 0.25h;
DOI:10.1080/24701556.2021.1980039
Guidance literature:
phosphoric acid; silica gel; at 60 - 70 ℃; for 0.166667h;
DOI:10.3987/COM-06-10783
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