2-Amino-5-chlorobenzophenone oxime

Base Information

• Chemical Name: 2-Amino-5-chlorobenzophenone oxime
• CAS No.: 15185-66-7
• Molecular Formula: C13H11ClN2O
• Molecular Weight: 246.696
• European Community (EC) Number: 241-999-5
• UNII: A4AZJ6W4EQ
• DSSTox Substance ID: DTXSID901230398
• Nikkaji Number: J153.949C
• ChEMBL ID: CHEMBL3208177
• Mol file: 15185-66-7.mol

Synonyms:2-Amino-5-chlorobenzophenone oxime;18097-52-4;(2-Amino-5-chlorophenyl)(phenyl)methanone oxime;Methanone, (2-amino-5-chlorophenyl)phenyl-, oxime;(1E)-(2-Amino-5-chlorophenyl)phenylmethanone oxime;Benzophenone, 2-amino-5-chloro-, oxime;(2-Amino-5-chlorophenyl)phenylmethanone oxime;4-chloro-2-[(hydroxyimino)(phenyl)methyl]aniline;(Z)-2-Amino-5-chlorobenzophenone oxime;A4AZJ6W4EQ;MLS000078203;2-Amino-5-chlorbenzophenonoxim;CHEMBL3208177;HMS551D11;CHEBI:190626;GCAVNCINXJNLED-DTQAZKPQSA-N;DTXSID901230398;(NE)-N-[(2-amino-5-chlorophenyl)-phenylmethylidene]hydroxylamine;CCG-48409;STK806178;AKOS000279605;CS-T-02287;anti-2-Amino-5-chlorobenzophenone oxime;SMR000034150;2-Amino-5-chlorobenzophenone oxime, (E)-;Benzophenone, 2-amino-5-chloro-, oxime, (E)-;(2-Amino-5-chloro-phenyl)-phenyl-methanone oxime;2-Amino-5-chlorobenzophenone I+/--oxime-, (Z)-;A812573;SR-01000414316;SR-01000414316-1;SR-01000414316-2;W-109174;4-chloro-2-[(E)-(hydroxyimino)(phenyl)methyl]aniline;(E)-(2-Amino-5-chlorophenyl)(phenyl)methanone oxime #;Methanone, (2-amino-5-chlorophenyl)phenyl-, oxime, (1E)-;Methanone, (2-amino-5-chlorophenyl)phenyl-, oxime, (E)-;(E)-N-[(2-amino-5-chlorophenyl)-phenylmethylidene]hydroxylamine

Chemical Property of 2-Amino-5-chlorobenzophenone oxime

Chemical Property:

• PSA: 58.61000
• LogP: 3.73000
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 246.0559907
• Heavy Atom Count: 17
• Complexity: 277

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NO)C2=C(C=CC(=C2)Cl)N
• Isomeric SMILES: C1=CC=C(C=C1)/C(=N\O)/C2=C(C=CC(=C2)Cl)N

Technology Process of 2-Amino-5-chlorobenzophenone oxime

There total 3 articles about 2-Amino-5-chlorobenzophenone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-aminobenzophenone (719-59-5) → (2-amino-5-chlorophenyl)(phenyl)methanone oxime (15185-66-7) + 2-amino-5-chlorobenzophenone α-oxime-(z) (5013-10-5)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In methanol; Inert atmosphere; Reflux;

DOI:10.1021/ol800053f

Reference yield:

5-chloro-2-aminobenzophenone (719-59-5) → (2-amino-5-chlorophenyl)(phenyl)methanone oxime (15185-66-7)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; Reflux;

Reference yield:

→ (2-amino-5-chlorophenyl)(phenyl)methanone oxime (15185-66-7)

Guidance literature:

Hydrolyse v. 6-Chlor-1.2-dihydro-2.2-dimethyl-4-phenyl-chinazolin-3-oxid m. wss.HCl;

DOI:10.1021/jo01022a519

upstream raw materials:

5-chloro-2-aminobenzophenone

Downstream raw materials:

7-chloro-5-phenyl-3-propyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

7-chloro-2-oxo-5-phenyl-3-propyl-2,3-dihydro-1H-1,4-benzodiazepin-4-ium-4-olate

Refernces

• 1、 Counceller, Carla M.,Eichman, Chad C.,Wray, Brertda C.,Stambuli, James P.. "A practical, metal-free synthesis of 1H-Lndazoles". supporting information; experimental part. p. 1021 - 1023. Retrieved 2009/04/07.