2-(Decylamino)ethanol

Base Information

• Chemical Name: 2-(Decylamino)ethanol
• CAS No.: 15196-28-8
• Molecular Formula: C12H27NO
• Molecular Weight: 201.352
• DSSTox Substance ID: DTXSID00398898
• Wikidata: Q82201145
• ChEMBL ID: CHEMBL241385
• Mol file: 15196-28-8.mol

Synonyms:2-(decylamino)ethanol;N-Decylaminoethanol;15196-28-8;N-Decyl Ethanolamine;N-decyl-amino ethanol;2-(decylamino)ethan-1-ol;SCHEMBL308701;CHEMBL241385;DTXSID00398898;PJNIZPXBKOEEGD-UHFFFAOYSA-N;AKOS009023645;FT-0665562;J-008870

Chemical Property of 2-(Decylamino)ethanol

Chemical Property:

• Vapor Pressure: 6.1E-05mmHg at 25°C
• Melting Point: 50-54 °C(Solv: methanol (67-56-1); chloroform (67-66-3))
• Boiling Point: 308.7oC at 760 mmHg
• PKA: 14.80±0.10(Predicted)
• Flash Point: 67.5oC
• PSA: 32.26000
• Density: 0.864g/cm3
• LogP: 3.09990
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly)
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 11
• Exact Mass: 201.209264485
• Heavy Atom Count: 14
• Complexity: 96.3

Purity/Quality:

98%, ^*data from raw suppliers

N-Decylaminoethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCNCCO
• Uses: N-DecylaMinoethanol is used in the antileishmanial activity of lipidic amino alcohols.

Technology Process of 2-(Decylamino)ethanol

There total 7 articles about 2-(Decylamino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

decyl chloride (1002-69-3) + ethanolamine (141-43-5) → 2-(n-Decylamino)ethanol (15196-28-8)

Guidance literature:

In ethanol; for 24h; Reflux;

DOI:10.1016/j.ejmech.2015.11.037

Reference yield:

caprinaldehyde (112-31-2) + ethanolamine (141-43-5) → 2-(n-Decylamino)ethanol (15196-28-8)

Guidance literature:

With hydrogen; platinum on activated charcoal; In methanol; at 20 ℃; for 16h; under 2280.15 Torr; Autoclave;

Reference yield:

methanesulfonic acid decyl ester (41233-29-8) + ethanolamine (141-43-5) → 2-(n-Decylamino)ethanol (15196-28-8)

Guidance literature:

In ethanol; Reflux;

DOI:10.1111/j.1747-0285.2009.00923.x

upstream raw materials:

methanesulfonic acid decyl ester

ethanolamine

1-bromo dodecane

caprinaldehyde

Downstream raw materials:

N-(9-fluorenylmethoxycarbonyl)-N-n-decylaminoethanol

N-decyl-N-(2-oxoethyl)carbamic acid 9H-fluoren-9-ylmethyl ester

Refernces

• 1、 De Souza Fernandes, Fábio,Fernandes, Tayrine Silva,Da Silveira, Lígia Souza,Caneschi, Wiliam,Louren?o, Maria Cristina S.,Diniz, Claudio G.,De Oliveira, Pollyanna Francielli,Martins, Sabrina De Paula Lima,Pereira, Daiane Eleutério,Tavares, Denise Crispim,Le Hyaric, Mireille,De Almeida, Mauro V.,Couri, Mara Rubia C.. "Synthesis and evaluation of antibacterial and antitumor activities of new galactopyranosylated amino alcohols". . p. 203 - 210. Retrieved 2016.
• 2、 -. "Synthesis method of special-pulling universal intermediate (by machine translation)". Paragraph 0024; 0039-0042. . Retrieved 2020/06/20.
• 3、 Guan, Dongliang,Chen, Feifei,Xiong, Lun,Tang, Feng,Faridoon,Qiu, Yunguang,Zhang, Naixia,Gong, Likun,Li, Jian,Lan, Lefu,Huang, Wei. "Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci". supporting information. p. 286 - 304. Retrieved 2018/02/10.