3-Methoxy-2-nitro-5-phenylpyridine

Base Information

Chemical Name:3-Methoxy-2-nitro-5-phenylpyridine
CAS No.:152684-17-8
Molecular Formula:C12H10N2O3
Molecular Weight:230.223
Hs Code.:
DSSTox Substance ID:DTXSID501295542
Nikkaji Number:J1.679.981E
Mol file:152684-17-8.mol

Synonyms:3-Methoxy-2-nitro-5-phenylpyridine;152684-17-8;DTXSID501295542;CGA68417;CS-B1199;2-Nitro-3-methoxy-5-phenylpyridine;AKOS026674225;Y10571

Suppliers and Price of 3-Methoxy-2-nitro-5-phenylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Methoxy-2-nitro-5-phenylpyridine 95+%
1g
$ 880.00

Crysdot
3-Methoxy-2-nitro-5-phenylpyridine 95+%
250mg
$ 352.00

ChemScene
Pyridine,3-methoxy-2-nitro-5-phenyl-
100mg
$ 289.00

Chemenu
3-Methoxy-2-nitro-5-phenylpyridine 95%
1g
$ 823.00

Total 6 raw suppliers

Chemical Property of 3-Methoxy-2-nitro-5-phenylpyridine

Chemical Property:

PSA：67.94000
LogP:3.18860
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:230.06914219
Heavy Atom Count:17
Complexity:261

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-Methoxy-2-nitro-5-phenylpyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(N=CC(=C1)C2=CC=CC=C2)[N+](=O)[O-]

Technology Process of 3-Methoxy-2-nitro-5-phenylpyridine

There total 4 articles about 3-Methoxy-2-nitro-5-phenylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 152684-26-9
5-bromo-3-methoxy-2-nitropyridine

: 98-80-6
phenylboronic acid

: 152684-17-8
3-methoxy-2-nitro-5-phenylpyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; benzene; for 2h; Heating;

Reference yield: 43.0%

: 152684-28-1
5-chloro-3-methoxy-2-nitropyridine

: 98-80-6
phenylboronic acid

: 152684-17-8
3-methoxy-2-nitro-5-phenylpyridine

Guidance literature:: With tetrabutylammomium bromide; potassium carbonate; di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino)ethyl]phenyl]palladium(II) dimer; In water; for 4h; Heating;
DOI:10.1002/1521-3773(20020104)41:1<179::AID-ANIE179>3.0.CO;2-O

Reference yield:

: 625-92-3
3,5-dibromopyridine

: 152684-17-8
3-methoxy-2-nitro-5-phenylpyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 50 percent / dimethylformamide / 2 h / 75 °C

2: 53 percent / H₂SO₄, HNO₃ / 1.5 h / 100 °C

3: 95 percent / (PPh₃)4Pd, Na₂CO₃ / benzene; ethanol / 2 h / Heating

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; nitric acid; sodium carbonate; In ethanol; N,N-dimethyl-formamide; benzene;