3-(1,3-Dioxolan-2-yl)benzonitrile, 97%

Base Information

• Chemical Name: 3-(1,3-Dioxolan-2-yl)benzonitrile, 97%
• CAS No.: 153329-04-5
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.187
• Hs Code.: 2932990090
• Mol file: 153329-04-5.mol

Synonyms:3-(1,3-dioxolan-2-yl)benzonitrile;2-(3-Cyanophenyl)-1,3-dioxolane;3-[1,3]dioxolan-2-yl-benzonitrile;

Chemical Property of 3-(1,3-Dioxolan-2-yl)benzonitrile, 97%

Chemical Property:

• PSA: 42.25000
• LogP: 1.60368

Purity/Quality:

85% ^*data from raw suppliers

3-(1,3-DIOXOLAN-2-YL)BENZONITRILE 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1,3-Dioxolan-2-yl)benzonitrile, 97%

There total 8 articles about 3-(1,3-Dioxolan-2-yl)benzonitrile, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-Cyanobenzaldehyde (24964-64-5) → 3-(1,3-dioxolan-2-yl)-benzonitrile (153329-04-5)

Guidance literature:

With p-toluenesulfonic acid monohydrate; In ethylene glycol; toluene;

Reference yield: 97.0%

3-Cyanobenzaldehyde (24964-64-5) + ethylene glycol (107-21-1) → 3-(1,3-dioxolan-2-yl)-benzonitrile (153329-04-5)

Guidance literature:

With sodium hydrogen sulfate; silica gel; for 0.05h; microwave irradiation;

Reference yield: 85.0%

3-(1,3-dioxolan-2-yl)-phenylbromide (17789-14-9) + 2,2-dimethylmalononitrile (7321-55-3) → 3-(1,3-dioxolan-2-yl)-benzonitrile (153329-04-5)

Guidance literature:

3-(1,3-dioxolan-2-yl)-phenylbromide; With magnesium; lithium chloride; In tetrahydrofuran; at 23 ℃;

2,2-dimethylmalononitrile; In tetrahydrofuran; at 0 - 23 ℃; for 0.5h;

DOI:10.1021/jacs.5b06136

upstream raw materials:

3-(1,3-dioxolan-2-yl)-phenylbromide

P-toluenesulfonyl cyanide

3-Cyanobenzaldehyde

ethylene glycol

Downstream raw materials:

3-Cyanobenzaldehyde

3-(1,3-dioxolan-2-yl)benzylamine

t-butyl N-(3-formylbenzyl)carbamate

tert-butyl [3-(1,3-dioxolan-2-yl)benzyl]carbamate