2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether

Base Information

• Chemical Name: 2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether
• CAS No.: 77197-90-1
• Molecular Formula: C₁₅H₁₂N₂O₅
• Molecular Weight: 300.271
• Mol file: 77197-90-1.mol

Synonyms:

Chemical Property of 2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether

There total 2 articles about 2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.9%

2-cyclopropylphenyl phenyl ether (75850-34-9) → 2-nitrophenyl 2-cyclopropylphenyl ether (77197-91-2) + 4-nitro-2-cyclopropylphenyl phenyl ether (77197-98-9) + 5-hydroxy-2-cyclopropyl-4-nitrophenyl phenyl ether (77197-89-8) + 2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether (77197-90-1)

Guidance literature:

With nitric acid; acetic anhydride; at -10 ℃; for 4h;

Reference yield:

phenol (108-95-2,27073-41-2) → 2-nitrophenyl 4-nitro-2-cyclopropylphenyl ether (77197-90-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / KOH, Cu / 2 h / 180 - 200 °C

2: 18.8 percent / 55percent aq. HNO₃, acetic anhydride / 4 h / -10 °C / other concentration of HNO₃; other temperature: -50 deg C; other reaction time: 2 h

With potassium hydroxide; nitric acid; acetic anhydride; copper;

upstream raw materials:

2-cyclopropylphenyl phenyl ether

phenol