7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester

Base Information

Chemical Name:7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester
CAS No.:153789-13-0
Molecular Formula:C11H19NO2
Molecular Weight:197.277
Hs Code.:
DSSTox Substance ID:DTXSID00448786
Nikkaji Number:J1.555.951I
Mol file:153789-13-0.mol

Synonyms:153789-13-0;Tert-butyl 7-azabicyclo[4.1.0]heptane-7-carboxylate;7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester;7-AZA-BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER;SCHEMBL3091698;DTXSID00448786;AKOS015968477;AS-40237;N-BOC-7-AZABICYCLO[4.1.0]HEPTANE;CS-0438637;Tert-butyl7-azabicyclo[4.1.0]heptane-7-carboxylate;7-(tert-Butoxycarbonyl)-7-azabicyclo[4.1.0]heptane

Suppliers and Price of 7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl7-azabicyclo[4.1.0]heptane-7-carboxylate 95+%
1g
$ 972.00

Chemenu
tert-Butyl7-azabicyclo[4.1.0]heptane-7-carboxylate 95%
1g
$ 916.00

Total 6 raw suppliers

Chemical Property of 7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester

Chemical Property:

PSA：29.31000
LogP:2.48620
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:197.141578849
Heavy Atom Count:14
Complexity:232

Purity/Quality:

95% ^*data from raw suppliers

tert-Butyl7-azabicyclo[4.1.0]heptane-7-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C2C1CCCC2

Technology Process of 7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester

There total 7 articles about 7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 477584-30-8
tert-butyl 2-hydroxycyclohexylcarbamate

: 153789-13-0
tert-butyl 7-azabicyclo<4.1.0>heptane-7-carboxylate

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 2 - 4h;

Reference yield: 70.0%

: 286-18-0
7-azabicyclo[4.1.0]heptane

: 24424-99-5
di-tert-butyl dicarbonate

: 153789-13-0
tert-butyl 7-azabicyclo<4.1.0>heptane-7-carboxylate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/S0040-4020(02)00729-9

Reference yield:

: 477584-30-8
tert-butyl [(1RS,2RS)-2-hydroxycyclohexyl]carbamate

: 153789-13-0
tert-butyl 7-azabicyclo<4.1.0>heptane-7-carboxylate

Guidance literature:: With azodicarboxylic acid bis(2-methoxyethyl) ester; triphenylphosphine; In tetrahydrofuran; at 0 - 35 ℃; for 3h; Inert atmosphere;