1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline

Base Information

• Chemical Name: 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline
• CAS No.: 109470-07-7
• Molecular Formula: C₁₇H₁₇NO
• Molecular Weight: 251.328
• Mol file: 109470-07-7.mol

Synonyms:

Chemical Property of 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline

There total 7 articles about 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-methylquinoline (612-60-2) → 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline (109470-07-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic NaOH-solution; nickel-aluminium-alloy

With sodium hydroxide; aluminum nickel;

DOI:10.1039/jr9580000614

Reference yield:

2,4-dichloro-7-methylquinoline (102878-19-3) → 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline (109470-07-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous hydrochloric acid; tin

With hydrogenchloride; tin;

DOI:10.1039/jr9580000614

Reference yield:

2-amino-7-methyl-quinolin-4-ol (103037-94-1) → 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline (109470-07-7)

Guidance literature:

Multi-step reaction with 6 steps

1: acetic acid; bromine

2: sodium nitrite; concentrated sulfuric acid

3: Raney alloy; water; NaOH-solution / 90 °C

4: phosphoryl chloride

5: aqueous hydrochloric acid; tin

With hydrogenchloride; sodium hydroxide; tin; sulfuric acid; water; bromine; nickel; acetic acid; sodium nitrite; trichlorophosphate;

DOI:10.1039/jr9580000614

upstream raw materials:

7-methyl-1,2,3,4-tetrahydroquinoline

7-methylquinoline

2,4-dichloro-7-methylquinoline

2-amino-7-methyl-quinolin-4-ol