4-Chloro-8-methoxyquinazoline

Base Information

Chemical Name:4-Chloro-8-methoxyquinazoline
CAS No.:154288-09-2
Molecular Formula:C9H7ClN2O
Molecular Weight:194.62
Hs Code.:
European Community (EC) Number:818-715-9
DSSTox Substance ID:DTXSID20437475
Mol file:154288-09-2.mol

Synonyms:4-CHLORO-8-METHOXYQUINAZOLINE;154288-09-2;Quinazoline, 4-chloro-8-methoxy-;MFCD09954869;4-chloro-8-methoxy-quinazoline;SCHEMBL857736;AMY9013;DTXSID20437475;BIGSOYZPKXOBJZ-UHFFFAOYSA-N;BCP34539;CS-D0029;AKOS006313204;DS-10851;SY031669;FT-0696007;EN300-1167035;J-515138;Z1198266476

Suppliers and Price of 4-Chloro-8-methoxyquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloro-8-methoxyquinazoline
5g
$ 1900.00

SynChem
4-CHLORO-8-METHOXYQUINAZOLINE 95%
1 g
$ 333.00

Matrix Scientific
4-Chloro-8-methoxyquinazoline 95+%
250mg
$ 324.00

Matrix Scientific
4-Chloro-8-methoxyquinazoline 95+%
1g
$ 700.00

Crysdot
4-Chloro-8-methoxyquinazoline 95+%
10g
$ 970.00

Crysdot
4-Chloro-8-methoxyquinazoline 95+%
5g
$ 581.00

Crysdot
4-Chloro-8-methoxyquinazoline 95+%
25g
$ 1743.00

Chemenu
4-chloro-8-methoxyquinazoline 95%
5g
$ 713.00

Chemenu
4-chloro-8-methoxyquinazoline 95%
10g
$ 1192.00

Chemenu
4-chloro-8-methoxyquinazoline 95%
1g
$ 238.00

Total 31 raw suppliers

Chemical Property of 4-Chloro-8-methoxyquinazoline

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Boiling Point:322.973oC at 760 mmHg
PKA:0.42±0.30(Predicted)
Flash Point:149.129oC
PSA：35.01000
Density:1.333g/cm3
LogP:2.29180
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:194.0246905
Heavy Atom Count:13
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

4-chloro-8-methoxyquinazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC2=C1N=CN=C2Cl
Uses 4-Chloro-8-methoxyquinazoline is used in preparation of of Quinazoline derivatives as Ectonucleotide Pyrophosphatase Phosphodiesterase 1 inhibitors.

Technology Process of 4-Chloro-8-methoxyquinazoline

There total 3 articles about 4-Chloro-8-methoxyquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 16064-27-0
8-methoxy-quinazolin-4(3H)-one

: 154288-09-2
4-chloro-8-methoxyquinazoline

Guidance literature:: With trichlorophosphate; for 3h; Heating;
DOI:10.1021/jm00039a024

Reference yield:

: 5121-34-6
methyl 2-amino-3-methoxybenzoate

: 154288-09-2
4-chloro-8-methoxyquinazoline

Guidance literature:: Multi-step reaction with 2 steps

2: trichlorophosphate

With trichlorophosphate; 1: |Niementowski Quinazolone Synthesis;
DOI:10.1039/c4md00113c