N-benzyl-1-(3-methylphenyl)methanamine

Base Information

• Chemical Name: N-benzyl-1-(3-methylphenyl)methanamine
• CAS No.: 15429-17-1
• Molecular Formula: C15H17N
• Molecular Weight: 211.307
• Mol file: 15429-17-1.mol

Synonyms:

Chemical Property of N-benzyl-1-(3-methylphenyl)methanamine

Chemical Property:

• Vapor Pressure: 0.000283mmHg at 25°C

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-benzyl-1-(3-methylphenyl)methanamine

There total 14 articles about N-benzyl-1-(3-methylphenyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-Methylbenzonitrile (620-22-4) + benzylamine (100-46-9) → N-benzyl-1-(m-tolyl)methanamine (15429-17-1)

Guidance literature:

With 1,3,2-oxazaborolidine-borane; copper(II) bis(trifluoromethanesulfonate); In water; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.joc.1c02413

Reference yield: 88.0%

3-methylbenzyl alcohol (587-03-1) + benzonitrile (100-47-0) → N-benzyl-1-(m-tolyl)methanamine (15429-17-1)

Guidance literature:

With rhodium(III) chloride hydrate; potassium carbonate; triphenylphosphine; at 140 ℃; for 9h; Inert atmosphere;

DOI:10.1002/chem.201003095

Reference yield: 79.0%

3-methyl-benzenemethanamine (100-81-2) + benzyl alcohol (100-51-6,185532-71-2) → C15H15N + N-benzyl-1-(m-tolyl)methanamine (15429-17-1)

Guidance literature:

With C₂₆H₃₀N₂NiO₃; sodium hydroxide; In toluene; for 20h; Reflux; Molecular sieve; Inert atmosphere;

DOI:10.1021/acs.organomet.1c00552

upstream raw materials:

1-bromomethyl-3-methyl-benzene

benzylamine

benzyl-(3-methyl-benzyliden)-amine

m-tolyl aldehyde

Refernces

• 1、 Han, Zhangang,Hao, Zhiqiang,Lin, Jin,Lu, Guo-Liang,Zhang, Junhua,Zhang, Xiaoying. "Nickel Complexes Bearing N,N,O-Tridentate Salicylaldiminato Ligand: Efficient Catalysts for Imines Formation via Dehydrogenative Coupling of Primary Alcohols with Amines". . p. 3843 - 3853. Retrieved 2021/11/18.
• 2、 Chen, Wen,Ren, Jian,Wang, Minshou,Dang, Lingjing,Shen, Xianfu,Yang, Xiaodong,Zhang, Hongbin. "Iodine mediated deprotection of N-tert-butanesulfinyl amines: A functional group compatible method". supporting information. p. 6259 - 6262. Retrieved 2014/06/09.