N-(4-fluorophenyl)-4-nitrobenzenesulfonamide

Base Information

Chemical Name:N-(4-fluorophenyl)-4-nitrobenzenesulfonamide
CAS No.:1545-96-6
Molecular Formula:C12H9FN2O4S
Molecular Weight:296.279
Hs Code.:
DSSTox Substance ID:DTXSID401255802
Nikkaji Number:J3.512.235D
ChEMBL ID:CHEMBL183392
Mol file:1545-96-6.mol

Synonyms:N-(4-fluorophenyl)-4-nitrobenzenesulfonamide;1545-96-6;Cambridge id 5328022;CHEMBL183392;SCHEMBL4574130;DTXSID401255802;BAA54596;MFCD00752545;STK121699;AKOS001637348;SB82601;N-(4-Nitrophenylsulfonyl)-4-fluoroaniline;BB 0303974;CS-0268368;J3.512.235D;AB00080937-01;SR-01000473784;SR-01000473784-1;Z45631371

Suppliers and Price of N-(4-fluorophenyl)-4-nitrobenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of N-(4-fluorophenyl)-4-nitrobenzenesulfonamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:296.02670611
Heavy Atom Count:20
Complexity:429

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-])F

Technology Process of N-(4-fluorophenyl)-4-nitrobenzenesulfonamide

There total 4 articles about N-(4-fluorophenyl)-4-nitrobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₁₉FN₂O₄S

: 1545-96-6
N-(4-fluorophenyl)-4-nitrobenzene sulphonamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere;
DOI:10.1016/j.jfluchem.2015.07.030

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 1545-96-6
N-(4-fluorophenyl)-4-nitrobenzene sulphonamide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 16 h / 0 - 20 °C / Inert atmosphere

2: [bis(acetoxy)iodo]benzene; pyridine hydrogenfluoride / dichloromethane / 0.25 h / 20 °C / Inert atmosphere

3: trifluoroacetic acid / dichloromethane / 0.08 h / 20 °C / Inert atmosphere

With pyridine; [bis(acetoxy)iodo]benzene; pyridine hydrogenfluoride; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.jfluchem.2015.07.030

Reference yield:

: N-(4-(tert-butyl)phenyl)-4-nitrobenzenesulfonamide

: 1545-96-6
N-(4-fluorophenyl)-4-nitrobenzene sulphonamide

Guidance literature:: Multi-step reaction with 2 steps

1: [bis(acetoxy)iodo]benzene; pyridine hydrogenfluoride / dichloromethane / 0.25 h / 20 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 0.08 h / 20 °C / Inert atmosphere

With [bis(acetoxy)iodo]benzene; pyridine hydrogenfluoride; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.jfluchem.2015.07.030