(S)-(2-oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate

Base Information

• Chemical Name: (S)-(2-oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate
• CAS No.: 154669-49-5
• Molecular Formula: C11H13NO5S
• Molecular Weight: 271.294
• DSSTox Substance ID: DTXSID80452720
• Nikkaji Number: J612.834C
• Wikidata: Q82273517

Synonyms:154669-49-5;(S)-(2-oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate;[(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl 4-methylbenzenesulfonate;2-Oxazolidinone, 4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, (4S)-;((4s)-2-oxo-1,3-oxazolidin-4-yl)methyl 4-methylbenzenesulfonate;SCHEMBL450129;DTXSID80452720;XZXRYNVWWTZADH-VIFPVBQESA-N;BS-53241;CS-0528841;(4S)-4alpha-(Tosyloxymethyl)oxazolidine-2-one;F73016;(s)-(2-oxo-oxazolidin-4-yl)methyl 4-methylbenzenesulfonate

Chemical Property of (S)-(2-oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 271.05144369
• Heavy Atom Count: 18
• Complexity: 394

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC2COC(=O)N2
• Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC[C@@H]2COC(=O)N2

Technology Process of (S)-(2-oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate

There total 1 articles about (S)-(2-oxooxazolidin-4-yl)methyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(4R)-4-(hydroxymethyl)-1,3-oxazolidin-2-one (132682-23-6) + p-toluenesulfonyl chloride (98-59-9) → [(S)-2-oxooxazolidin-4-yl]methyl-4-methylbenzenesulfonate (154669-49-5)

Guidance literature:

In pyridine; at 20 ℃;

DOI:10.1016/j.tetlet.2006.03.089

Reference yield: 97.0%

p-methoxyphenyllithium (14774-77-7) + [(S)-2-oxooxazolidin-4-yl]methyl-4-methylbenzenesulfonate (154669-49-5) → (R)-4-(4-methoxybenzyl)oxazolidin-2-one

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; 1.) -78 deg C, 30 min, 2.) room temperature, 7.5 h;

Reference yield: 95.0%

[(S)-2-oxooxazolidin-4-yl]methyl-4-methylbenzenesulfonate (154669-49-5) → (S)-(-)-4-iodomethyl-2-oxazolidinone (132682-24-7)

Guidance literature:

With sodium iodide; In acetone; for 5h; Heating;

DOI:10.1021/ja9906249

upstream raw materials:

(4R)-4-(hydroxymethyl)-1,3-oxazolidin-2-one

p-toluenesulfonyl chloride

Downstream raw materials:

(R)-4-propyloxazolidin-2-one

(4R)-4-methyl-1,3-oxazolidin-2-one

(R)-4-(phenylmethyl)-2-oxazolidinone

(S)-(-)-4-iodomethyl-2-oxazolidinone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 154669-49-5 2-Oxazolidinone, 4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, (4S)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send