3-benzoyl-2-phenyl-4H-chromen-4-one

Base Information

• Chemical Name: 3-benzoyl-2-phenyl-4H-chromen-4-one
• CAS No.: 5453-03-2
• Molecular Formula: C22H14 O3
• Molecular Weight: 326.351
• Mol file: 5453-03-2.mol

Synonyms:3-Benzoylflavone;NSC 19040

Chemical Property of 3-benzoyl-2-phenyl-4H-chromen-4-one

Chemical Property:

• Vapor Pressure: 1.75E-09mmHg at 25°C
• Boiling Point: 482.9°Cat760mmHg
• Flash Point: 213.1°C
• Density: 1.283g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-benzoyl-2-phenyl-4H-chromen-4-one

There total 26 articles about 3-benzoyl-2-phenyl-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-(Hydroxy-phenyl-methyl)-2-phenyl-chromen-4-one (119139-39-8) → 2-phenyl-3-benzoyl-4H-1-benzopyran-4-one (5453-03-2)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4020(88)90041-5

Reference yield: 88.0%

2-(3-phenylprop-2-ynoyl)phenyl benzoate (1415384-88-1) → 2-phenyl-3-benzoyl-4H-1-benzopyran-4-one (5453-03-2)

Guidance literature:

With 5,6,9,10-tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine; In N,N-dimethyl-formamide; at 30 ℃; for 6h; Reagent/catalyst; Time; regioselective reaction; Inert atmosphere;

DOI:10.1039/c2cc37015h

Reference yield: 82.0%

2-(3-phenylprop-2-ynoyl)phenyl benzoate (1415384-88-1) → FLAVONE (525-82-6,66585-04-4) + 2-phenyl-3-benzoyl-4H-1-benzopyran-4-one (5453-03-2)

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; In N,N-dimethyl-formamide; at 30 ℃; for 21h; Reagent/catalyst; Time; Solvent; Temperature; regioselective reaction; Inert atmosphere;

DOI:10.1039/c2cc37015h

upstream raw materials:

2'-hydroxy-2-benzoyl-3-phenyl-acrylophenone

o-hydroxyacetophenone

benzoic acid anhydride

2-acetylphenyl benzoate

Downstream raw materials:

3-benzylamino-1-(2-hydroxyphenyl)-3-phenyl-2-propenone

FLAVONE

3-iodo-2-phenyl-4H-1-benzopyran-4-one

3-benzylamino-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one