3-(2,4-Difluoroanilino)-3-oxopropanoic acid

Base Information

Chemical Name:3-(2,4-Difluoroanilino)-3-oxopropanoic acid
CAS No.:154935-07-6
Molecular Formula:C9H7F2NO3
Molecular Weight:215.156
Hs Code.:
DSSTox Substance ID:DTXSID50363192
Wikidata:Q82146786
Mol file:154935-07-6.mol

Synonyms:3-(2,4-difluoroanilino)-3-oxopropanoic acid;154935-07-6;Propanoic acid, 3-[(2,4-difluorophenyl)amino]-3-oxo-;2-[(2,4-difluorophenyl)carbamoyl]acetic Acid;Oprea1_303670;SCHEMBL8234531;DTXSID50363192;MFCD00201924;AKOS011514909;2-[(2,4-difluorophenyl)carbamoyl]aceticAcid;1E-086

Suppliers and Price of 3-(2,4-Difluoroanilino)-3-oxopropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(2,4-Difluoroanilino)-3-oxopropanoic acid
5g
$ 7343.00

Matrix Scientific
3-(2,4-Difluoroanilino)-3-oxopropanoic acid
1g
$ 1836.00

Matrix Scientific
3-(2,4-Difluoroanilino)-3-oxopropanoic acid
500mg
$ 918.00

American Custom Chemicals Corporation
3-(2,4-DIFLUOROANILINO)-3-OXOPROPANOIC ACID 95.00%
5MG
$ 697.51

American Custom Chemicals Corporation
3-(2,4-DIFLUOROANILINO)-3-OXOPROPANOIC ACID 95.00%
10MG
$ 692.49

American Custom Chemicals Corporation
3-(2,4-DIFLUOROANILINO)-3-OXOPROPANOIC ACID 95.00%
1MG
$ 658.53

Total 3 raw suppliers

Chemical Property of 3-(2,4-Difluoroanilino)-3-oxopropanoic acid

Chemical Property:

PSA：69.89000
LogP:2.02750
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:215.03939941
Heavy Atom Count:15
Complexity:260

Purity/Quality:

99% ^*data from raw suppliers

3-(2,4-Difluoroanilino)-3-oxopropanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)F)NC(=O)CC(=O)O

Technology Process of 3-(2,4-Difluoroanilino)-3-oxopropanoic acid

There total 5 articles about 3-(2,4-Difluoroanilino)-3-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

: 479690-12-5
N-(2,4-difluorophenyl)malonic acid methyl ester

: 154935-07-6
N-(2,4-difluorophenyl)malonic acid

Guidance literature:: N-(2,4-difluorophenyl)malonic acid methyl ester; With lithium hydroxide; In ethanol; for 3.5h;

With hydrogenchloride; In ethanol; water;

Reference yield:

: 145591-74-8
ethyl 3-[(2,4-difluorophenyl)amino]-3-oxopropanoate

: 154935-07-6
N-(2,4-difluorophenyl)malonic acid

Guidance literature:: ethyl 3-[(2,4-difluorophenyl)amino]-3-oxopropanoate; With methanol; sodium hydroxide; water; at 20 ℃; for 24h;

With hydrogenchloride; water; In ethyl acetate; pH=~ 5;

Reference yield:

: 367-25-9,76563-56-9
2,4-difluorophenylamine

: 36239-09-5
ethyl chlorocarbonylacetate

: 154935-07-6
N-(2,4-difluorophenyl)malonic acid

Guidance literature:: 2,4-difluorophenylamine; ethyl chlorocarbonylacetate; With potassium carbonate; In chloroform; at 20 ℃; for 0.166667h;

With lithium hydroxide; In ethanol; water; at 20 ℃; for 4h;

With hydrogenchloride; In water; at 0 ℃;