Methyl 3-[(chloroacetyl)amino]benzoate

Base Information

Chemical Name:Methyl 3-[(chloroacetyl)amino]benzoate
CAS No.:41653-05-8
Molecular Formula:C10H10 Cl N O3
Molecular Weight:227.647
Hs Code.:2924299090
DSSTox Substance ID:DTXSID80367921
Wikidata:Q82154108
Mol file:41653-05-8.mol

Synonyms:methyl 3-[(chloroacetyl)amino]benzoate;41653-05-8;methyl 3-(2-chloroacetamido)benzoate;methyl 3-[(2-chloroacetyl)amino]benzoate;SCHEMBL10913181;DTXSID80367921;FRBYDITWHMOOIR-UHFFFAOYSA-N;MFCD00522772;AKOS000295662;methyl 3-(2-chloroacetamido)-benzoate;LS-03669;methyl m-(alpha-chloroacetylamino)benzoate;CS-0308181;FT-0683307;EN300-11052;Z56895739

Suppliers and Price of Methyl 3-[(chloroacetyl)amino]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl3-[(Chloroacetyl)amino]benzoate
50mg
$ 45.00

American Custom Chemicals Corporation
METHYL 3-[(CHLOROACETYL)AMINO]BENZOATE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
METHYL 3-[(CHLOROACETYL)AMINO]BENZOATE 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
METHYL 3-[(CHLOROACETYL)AMINO]BENZOATE 95.00%
1G
$ 692.46

Alichem
Methyl3-(2-chloroacetamido)benzoate
5g
$ 400.00

AK Scientific
Methyl3-[(chloroacetyl)amino]benzoate
500mg
$ 178.00

Total 5 raw suppliers

Chemical Property of Methyl 3-[(chloroacetyl)amino]benzoate

Chemical Property:

Vapor Pressure:6.41E-07mmHg at 25°C
Boiling Point:409.6°C at 760 mmHg
Flash Point:201.5°C
PSA：55.40000
Density:1.325g/cm³
LogP:1.72350
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:227.0349209
Heavy Atom Count:15
Complexity:245

Purity/Quality:

98%min ^*data from raw suppliers

Methyl3-[(Chloroacetyl)amino]benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=CC=C1)NC(=O)CCl

Technology Process of Methyl 3-[(chloroacetyl)amino]benzoate

There total 3 articles about Methyl 3-[(chloroacetyl)amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 4518-10-9
Methyl 3-aminobenzoate

: 79-04-9
chloroacetyl chloride

: 41653-05-8
methyl 3-(2-chloroacetamido)benzoate

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 4h;
DOI:10.1021/acs.jmedchem.7b00587

Reference yield:

: 99-05-8,159139-79-4
meta-aminobenzoic acid

: 41653-05-8
methyl 3-(2-chloroacetamido)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 4 h / 0 - 90 °C

2: triethylamine / dichloromethane / 12 h / 20 °C

With thionyl chloride; triethylamine; In dichloromethane;
DOI:10.5012/bkcs.2011.32.12.4444