Hexaethylene glycol monohexadecyl ether

Base Information

• Chemical Name: Hexaethylene glycol monohexadecyl ether
• CAS No.: 5168-91-2
• Molecular Formula: C28H58 O7
• Molecular Weight: 506.76
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID10965959
• Nikkaji Number: J641.570I
• Wikidata: Q82948286
• Mol file: 5168-91-2.mol

Synonyms:Hexaethylene glycol monohexadecyl ether;5168-91-2;Procol ca-6;HEXAETHYLENEGLYCOLMONOHEXADECYLETHER;Ceteth-6 [INCI];Nikkol BC-5.5;2-[2-[2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol;3,6,9,12,15,18-Hexaoxatetratriacontan-1-ol;UNII-3GK4XZK07U;3GK4XZK07U;SCHEMBL60936;DTXSID10965959;hexaethyleneglycol monohexadecyl ether;HY-W250179;CS-0256355;FT-0750755;Hexaethylene glycol monohexadecyl ether, BioXtra, >=99.0% (TLC)

Chemical Property of Hexaethylene glycol monohexadecyl ether

Chemical Property:

• Vapor Pressure: 3.01E-15mmHg at 25°C
• Melting Point: 39-40 °C
• Boiling Point: 567.6oC at 760mmHg
• Flash Point: 297.1oC
• PSA: 75.61000
• Density: 0.962 g/cm3
• LogP: 5.55960
• XLogP3: 6.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 32
• Exact Mass: 506.41825418
• Heavy Atom Count: 35
• Complexity: 358

Purity/Quality:

98%+ ^*data from raw suppliers

Hexaethylene glycol monohexadecyl ether non-ionic ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCO

Technology Process of Hexaethylene glycol monohexadecyl ether

There total 7 articles about Hexaethylene glycol monohexadecyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triethyleneglycol-mono-n-hexadecyl ether (4484-59-7,39290-55-6,53663-60-8,8038-99-1,9004-95-9) → hexaethylene glycol mono n-hexadecyl ether (5168-91-2,39290-55-6,53663-60-8,8038-99-1,9004-95-9)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether

2: 1.) sodium / 1.) 70-100 deg C

With sodium; triethylamine; In diethyl ether;

Reference yield:

hexadecanyl bromide (112-82-3) → hexaethylene glycol mono n-hexadecyl ether (5168-91-2,39290-55-6,53663-60-8,8038-99-1,9004-95-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) sodium / 1.) 70-100 deg C

2: triethylamine / diethyl ether

3: 1.) sodium / 1.) 70-100 deg C

With sodium; triethylamine; In diethyl ether;

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → hexaethylene glycol mono n-hexadecyl ether (5168-91-2,39290-55-6,53663-60-8,8038-99-1,9004-95-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) sodium / 1.) 70-100 deg C

2: triethylamine / diethyl ether

3: 1.) sodium / 1.) 70-100 deg C

With sodium; triethylamine; In diethyl ether;

upstream raw materials:

pentaethylene glycol

hexadecanyl bromide

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

1-Chlorohexadecan

Downstream raw materials:

hexaethyleneglycol monohexadecyl ether p-toluenesulfonate

Refernces

• 1、 Bethell, Donald,Galsworthy, Peter J.,Jones, Keith. "Mutarotation of Glucose Derivatives in Solutions of Surfactans in Organic Solvents: Co-operativity and Bimodal Catalytic Behaviour". . p. 2035 - 2044. Retrieved 2007/10/02.