2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid

Base Information

Chemical Name:2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid
CAS No.:157874-97-0
Molecular Formula:C₁₅H₁₄O₄
Molecular Weight:258.274
Hs Code.:
UNII:9UI6LCM2KW
DSSTox Substance ID:DTXSID50870053
Nikkaji Number:J1.320.864F
Wikidata:Q27273243
Mol file:157874-97-0.mol

Synonyms:2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid;UNII-9UI6LCM2KW;9UI6LCM2KW;157874-97-0;Benzeneacetic acid, alpha-hydroxy-alpha-methyl-4-phenoxy-;Benzeneacetic acid, .alpha.-hydroxy-.alpha.-methyl-4-phenoxy-;IN-JS940;SCHEMBL8780675;DTXSID50870053;alpha-Hydroxy-alpha-methyl-4-phenoxybenzeneacetic acid;Q27273243

Suppliers and Price of 2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:258.08920892
Heavy Atom Count:19
Complexity:303

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)OC2=CC=CC=C2)(C(=O)O)O

Technology Process of 2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid

There total 1 articles about 2-hydroxy-2-(4-phenoxyphenyl)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 917-64-6
methyl magnesium iodide

: 79478-16-3
(4-Phenoxy)phenylglyoxylsaeure

: 157874-97-0
2-Hydroxy-2-(4-phenoxyphenyl)propansaeure

Guidance literature:: In diethyl ether; for 1h; Heating;

Reference yield:

: 157874-97-0
2-Hydroxy-2-(4-phenoxyphenyl)propansaeure

: 1-Hydroxy-3-methyl-6-phenoxyindolin-2-on

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 1,1'-carbonyldiimidazole / 1.) CH₂Cl₂, 2.) CH₂Cl₂, r.t., 8 h

2: 67 percent / dicyclohexylcarbodiimide / trichloroethene / 18 h / 86 °C

3: 45 percent / 6N HCl / dioxane / 12 h / Heating

With hydrogenchloride; dicyclohexyl-carbodiimide; 1,1'-carbonyldiimidazole; In 1,4-dioxane; Trichloroethylene;

Reference yield:

: 157874-97-0
2-Hydroxy-2-(4-phenoxyphenyl)propansaeure

: 1-Methoxy-3-methyl-6-phenoxyindolin-2-on

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 1,1'-carbonyldiimidazole / 1.) CH₂Cl₂, 2.) CH₂Cl₂, r.t., 8 h

2: 56 percent / dicyclohexylcarbodiimide / trichloroethene / 3 h / 86 °C

With dicyclohexyl-carbodiimide; 1,1'-carbonyldiimidazole; In Trichloroethylene;