ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE

Base Information

• Chemical Name: ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE
• CAS No.: 156093-78-6
• Molecular Formula: C9H9NO3
• Molecular Weight: 179.17300
• Mol file: 156093-78-6.mol

Synonyms:ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE;Ethyl oxopyridin-4-ylacetate;oxopyridin-4-ylacetic acid ethyl ester;

Chemical Property of ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE

Chemical Property:

• Boiling Point: 284.7±13.0 °C(Predicted)
• PKA: 1.87±0.10(Predicted)
• PSA: 56.26000
• Density: 1.189±0.06 g/cm3(Predicted)
• LogP: 0.82740

Purity/Quality:

97% ^*data from raw suppliers

ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE

There total 2 articles about ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

pyridin-4-yl-acetic acid ethyl ester (54401-85-3) + [hydroxy(tosyloxy)iodo]benzene (27126-76-7) → oxo-pyridin-4-yl-acetic acid ethyl ester (156093-78-6) + Pyridin-4-yl-(toluene-4-sulfonyloxy)-acetic acid ethyl ester

Guidance literature:

In dichloromethane; at 20 ℃; for 48h;

Reference yield: 2.0%

pyridin-4-yl-acetic acid ethyl ester (54401-85-3) → oxo-pyridin-4-yl-acetic acid ethyl ester (156093-78-6) + Pyridin-4-yl-(toluene-4-sulfonyloxy)-acetic acid ethyl ester

Guidance literature:

With [hydroxy(tosyloxy)iodo]benzene; In dichloromethane; at 20 ℃; for 48h;

Reference yield:

(4-oxazol-5-yl-phenyl)-hydrazine (738570-45-1) + oxo-pyridin-4-yl-acetic acid ethyl ester (156093-78-6) → (Z)-2-[4-(oxazol-5-yl)phenylhydrazono]pyridin-4-ylacetic acid ethyl ester

Guidance literature:

With acetic acid; In water; at 20 ℃; for 2h;

upstream raw materials:

pyridin-4-yl-acetic acid ethyl ester

[hydroxy(tosyloxy)iodo]benzene