Chemical Property of [Hydroxy(tosyloxy)iodo]benzene
Chemical Property:
- Appearance/Colour:Pale yellow crystalline powder
- Melting Point:131-137 °C(lit.)
- PKA:7.59±0.58(Predicted)
- PSA：71.98000
- LogP:4.35980
- Storage Temp.:Refrigerator (+4°C)
- Sensitive.:Light Sensitive
- Solubility.:soluble in Methanol
- XLogP3:3.7
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:4
- Exact Mass:391.95793
- Heavy Atom Count:19
- Complexity:365
- Purity/Quality:
-
98%, *data from raw suppliers
[Hydroxy(tosyloxy)iodo]benzene *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OI(C2=CC=CC=C2)O
-
Uses
Versatile synthetic reagent in phenyliodination and/or tosylation of a range of organic substrates; in oxidative transformations including oxidative rearrangements. Reactant for:Ligand-free palladium-catalyzed Heck-type coupling reactionsPreparation of carbodiimides via dehydrosulfurization of thioureasPreparation of nitriles by oxidative conversion of alcohols, aldehydes, and aminesPreparation of substituted anilines via aromatic aldoxime reactionPreparation of tetrahydrofurans by oxidative cyclization of homoallylic alcoholsPreparation of isoxazoline N-Oxides from ?-hydroxyketoximes via oxidative N-O couplingRing expansion in synthesis of aminopeptidase inhibitorsOxidation and protonation reactions in acidic conditions
