2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl-

Base Information

Chemical Name:2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl-
CAS No.:156136-66-2
Molecular Formula:C₁₀H₁₁NO
Molecular Weight:161.203
Hs Code.:
DSSTox Substance ID:DTXSID10473443
Nikkaji Number:J1.958.229I
Wikidata:Q82302839
Mol file:156136-66-2.mol

Synonyms:1,6-Dimethylindolin-2-one;2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl-;1,6-dimethyl-3H-indol-2-one;156136-66-2;1,6-dimethyl-2-indolinone;SCHEMBL5986263;DTXSID10473443;MZDBULPTSUNKSC-UHFFFAOYSA-N

Suppliers and Price of 2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl-

Chemical Property:

PSA：20.31000
LogP:1.57890
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:161.084063974
Heavy Atom Count:12
Complexity:202

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(CC(=O)N2C)C=C1

Technology Process of 2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl-

There total 1 articles about 2H-Indol-2-one, 1,3-dihydro-1,6-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 2-diazo-3-[methyl-(p-tolyl)amino]-3-oxopropanoate

: 4559-70-0
Diphenylphosphine oxide

: 2-(diphenylphosphoryl)-N-methyl-N-(p-tolyl)acetamide

: 156136-66-2
1-methyl-6-methyl-1,3-dihydroindol-2-one

Guidance literature:: With water; copper diacetate; In 1,4-dioxane; at 100 ℃; for 3h; Sealed tube; Schlenk technique; Inert atmosphere;
DOI:10.1002/ejoc.202001326

Reference yield: 91.0%

: 156136-66-2
1-methyl-6-methyl-1,3-dihydroindol-2-one

: 156136-67-3
1,3-dihydro-1,6-dimethyl-2H-indole-2-thione

Guidance literature:: With tetraphosphorus decasulfide; sodium carbonate; In tetrahydrofuran; for 18h; Ambient temperature;
DOI:10.1021/jm00039a016

Reference yield:

: 156136-66-2
1-methyl-6-methyl-1,3-dihydroindol-2-one

: 1026534-91-7
1,6-Dimethyl-2-thioxo-2,3-dihydro-1H-indole-3-carboxylic acid phenylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / Na₂CO₃, P₂S₅ / tetrahydrofuran / 18 h / Ambient temperature

2: 1.) NaH / 1.) THF, 2.) THF

With tetraphosphorus decasulfide; sodium hydride; sodium carbonate; In tetrahydrofuran;
DOI:10.1021/jm00039a016