2-[(4-METHYLPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE

Base Information

• Chemical Name: 2-[(4-METHYLPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE
• CAS No.: 15875-51-1
• Molecular Formula: C17H12O2
• Molecular Weight: 248.281
• Mol file: 15875-51-1.mol

Synonyms:2-(4-methylbenzylidene)-2H-indene-1,3-dione;1H-indene-1,3(2H)-dione,2-[(4-methylphenyl)methylene];2-(4-methylbenzylidene)indane-1,3-dione;(4-methylbenzylidene)inden-1,3-dione;2-[(4-methylphenyl)methylene]cyclopenta[1,2-a]benzene-1,3-dione;2-(4-chlorobenzylidene)-2H-indene-1,3-dione;2-(4-methylbenzylidene)-1H-indene-1,3(2H)-dione;(E)-2-(4-methylbenzylidene)-1H-indene-1,3(2H)-dione;2-(p-methylbenzylidene)indane-1,3-dione;

Chemical Property of 2-[(4-METHYLPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE

Chemical Property:

• PSA: 34.14000
• LogP: 3.45760

Purity/Quality:

99% ^*data from raw suppliers

2-[(4-METHYLPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(4-METHYLPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE

There total 14 articles about 2-[(4-METHYLPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1H-indene-1,3(2H)-dione (606-23-5) + 4-methyl-benzaldehyde (104-87-0) → 2-(4-methyl-benzylidene)-indan-1,3-dione (15875-51-1)

Guidance literature:

With biosurfactant from Balanites roxburghii fruit; at 20 ℃; for 0.25h; Green chemistry;

DOI:10.1039/c4ra04387a

Reference yield: 89.0%

1H-indene-1,3(2H)-dione (606-23-5) + N-methyl-4-tolylnitrone (203861-67-0) → 2-(4-methyl-benzylidene)-indan-1,3-dione (15875-51-1)

Guidance literature:

In dichloromethane; at 80 ℃; for 2h; Sealed tube;

DOI:10.1016/j.tet.2012.06.086

Reference yield: 80.0%

1H-indene-1,3(2H)-dione (606-23-5) + 5-(4-methylbenzylidene)barbituric acid (56504-51-9) → 2-(4-methyl-benzylidene)-indan-1,3-dione (15875-51-1)

Guidance literature:

With piperidine; In ethanol; at 20 ℃; Reflux;

DOI:10.3987/COM-10-12073

upstream raw materials:

1H-indene-1,3(2H)-dione

4-methyl-benzaldehyde

indan-1,2-dione

(Z)-2-(4-Methylbenzylidene)-1-indanone

Downstream raw materials:

2',4'-dihydro-2',5'-diphenyl-4'-(4-methylphenyl) spiro[2H-indene-2,3'-[3H]pyrazole]-1,3-dione