1-Bromo-9H-pyrido[3,4-b]indole

Base Information

Chemical Name:1-Bromo-9H-pyrido[3,4-b]indole
CAS No.:159898-15-4
Molecular Formula:C11H7BrN2
Molecular Weight:247.094
Hs Code.:
DSSTox Substance ID:DTXSID40474160
Nikkaji Number:J2.039.954F
Wikidata:Q82303983

Synonyms:1-Bromo-9H-pyrido[3,4-b]indole;159898-15-4;9H-Pyrido[3,4-b]indole, 1-bromo-;1-bromo-beta-carboline;SCHEMBL26087436;DTXSID40474160;MFCD18449824;CS-0062553;D73236

Suppliers and Price of 1-Bromo-9H-pyrido[3,4-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
1-Bromo-9H-pyrido[3,4-b]indole 95%+
1g
$ 1857.00

Total 6 raw suppliers

Chemical Property of 1-Bromo-9H-pyrido[3,4-b]indole

Chemical Property:

PSA：28.68000
LogP:3.47860
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:245.97926
Heavy Atom Count:14
Complexity:221

Purity/Quality:

99.3% ^*data from raw suppliers

1-Bromo-9H-pyrido[3,4-b]indole 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=C(N2)C(=NC=C3)Br

Technology Process of 1-Bromo-9H-pyrido[3,4-b]indole

There total 3 articles about 1-Bromo-9H-pyrido[3,4-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 19839-52-2
2,9-dihydro-1H-pyrido[3,4-b]indol-1-one

: 159898-15-4
1-bromo-9H-pyrido<3,4-b>indole

Guidance literature:: With phosphorus(V) oxybromide; In various solvent(s); at 120 ℃; for 4h;
DOI:10.1016/S0040-4020(01)89542-9

Reference yield:

: 61-54-1
tryptamine

: 159898-15-4
1-bromo-9H-pyrido<3,4-b>indole

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / toluene / 1.08 h / 20 °C / Inert atmosphere

1.2: 1 h / Inert atmosphere; Reflux

2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 0.42 h / 15 - 20 °C / Inert atmosphere

3.1: phosphorus(V) oxybromide / Reflux

With triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; phosphorus(V) oxybromide; In 1,4-dioxane; toluene; 1.1: |Bischler-Napieralski Reaction / 1.2: |Bischler-Napieralski Reaction;
DOI:10.1016/j.bmcl.2014.05.049

Reference yield:

: 17952-82-8
1,2,3,4-tetrahydronorharman-1-one

: 159898-15-4
1-bromo-9H-pyrido<3,4-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 0.42 h / 15 - 20 °C / Inert atmosphere

2: phosphorus(V) oxybromide / Reflux

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; phosphorus(V) oxybromide; In 1,4-dioxane;
DOI:10.1016/j.bmcl.2014.05.049