Carbamic acid, [(1S,2R)-2-hydroxy-3-[(2-methylpropyl)(phenylsulfonyl)amino]-1-(phenyl methyl)propyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [(1S,2R)-2-hydroxy-3-[(2-methylpropyl)(phenylsulfonyl)amino]-1-(phenyl methyl)propyl]-, 1,1-dimethylethyl ester
CAS No.:160230-53-5
Molecular Formula:C25H36N2O5S
Molecular Weight:476.637
Hs Code.:
Mol file:160230-53-5.mol

Synonyms:

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Chemical Property of Carbamic acid, [(1S,2R)-2-hydroxy-3-[(2-methylpropyl)(phenylsulfonyl)amino]-1-(phenyl methyl)propyl]-, 1,1-dimethylethyl ester

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Technology Process of Carbamic acid, [(1S,2R)-2-hydroxy-3-[(2-methylpropyl)(phenylsulfonyl)amino]-1-(phenyl methyl)propyl]-, 1,1-dimethylethyl ester

There total 2 articles about Carbamic acid, [(1S,2R)-2-hydroxy-3-[(2-methylpropyl)(phenylsulfonyl)amino]-1-(phenyl methyl)propyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 160232-08-6
(2R,3S)-3-tert-butoxycarbonylamino-1-isobutylamino-4-phenyl-2-butanol

: 160230-53-5
[(1S,2R)-3-(Benzenesulfonyl-isobutyl-amino)-1-benzyl-2-hydroxy-propyl]-carbamic acid tert-butyl ester

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1021/jm049560p

Reference yield:

: 98760-08-8,98818-34-9,98818-35-0,103127-56-6,98737-29-2
(1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester

: 160230-53-5
[(1S,2R)-3-(Benzenesulfonyl-isobutyl-amino)-1-benzyl-2-hydroxy-propyl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: propan-2-ol / 2 h / 80 °C

2: triethylamine / CH₂Cl₂ / 20 °C

With triethylamine; In dichloromethane; isopropyl alcohol;
DOI:10.1016/j.bmc.2006.05.063