2,5-Oxazolidinedione, 3-methyl-4-(phenylmethyl)-4-(trifluoromethyl)-

Base Information

Chemical Name:2,5-Oxazolidinedione, 3-methyl-4-(phenylmethyl)-4-(trifluoromethyl)-
CAS No.:160511-12-6
Molecular Formula:C12H10F3NO3
Molecular Weight:273.20800
Hs Code.:
Mol file:160511-12-6.mol

Synonyms:2,5-Oxazolidinedione,3-methyl-4-(phenylmethyl)-4-(trifluoromethyl);

Suppliers and Price of 2,5-Oxazolidinedione, 3-methyl-4-(phenylmethyl)-4-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,5-Oxazolidinedione, 3-methyl-4-(phenylmethyl)-4-(trifluoromethyl)-

Chemical Property:

Boiling Point:288.8±43.0 °C(Predicted)
PSA：46.61000
Density:1.411±0.06 g/cm3(Predicted)
LogP:2.07670

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,5-Oxazolidinedione, 3-methyl-4-(phenylmethyl)-4-(trifluoromethyl)-

There total 1 articles about 2,5-Oxazolidinedione, 3-methyl-4-(phenylmethyl)-4-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139520-49-3
4-Benzyl-4-trifluoromethyl-oxazolidine-2,5-dione

: 74-88-4
methyl iodide

: 160511-12-6
4-benzyl-3-methyl-4-trifluoromethyl-oxazolidine-2,5-dione

Guidance literature:: 4-Benzyl-4-trifluoromethyl-oxazolidine-2,5-dione; With sodium hydride; In N,N-dimethyl-formamide;

methyl iodide; In N,N-dimethyl-formamide;
DOI:10.1021/jm0511334

Reference yield:

: 160511-12-6
4-benzyl-3-methyl-4-trifluoromethyl-oxazolidine-2,5-dione

: 161234-80-6
N⁵-[(phenylmethoxy)carbonyl]-L-ornithine 1,1-dimethylethyl ester hydrochloride

: 881853-75-4
5-benzyloxycarbonylamino-2-(2-benzyl-3,3,3-trifluoro-2-methylamino-propionylamino)-pentanoic acid tert-butyl ester

Guidance literature:: With TEA; In dichloromethane; at 20 ℃;
DOI:10.1021/jm0511334

Reference yield:

: 160511-12-6
4-benzyl-3-methyl-4-trifluoromethyl-oxazolidine-2,5-dione

: ((S)-2-{2-[((S)-2-Amino-3-phenyl-propionyl)-methyl-amino]-2-benzyl-3,3,3-trifluoro-propionylamino}-5-benzyloxycarbonylamino-pentanoylamino)-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: TEA / CH₂Cl₂ / 20 °C

2: 1-bromo-N,N,2-trimethyl-1,1-propenylamine; collidine / CH₂Cl₂ / 5 h

3: TFA / CH₂Cl₂ / 1 h

4: HOAT; DCC; DIEA / CH₂Cl₂ / 2 h

5: [Et₃NH][Sn(SPh)3] / acetonitrile / 1 h / 20 °C

With 2,3,5-trimethyl-pyridine; 1-hydroxy-7-aza-benzotriazole; 1-bromo-N,N,2-trimethyl-1-propen-1-amine; [Et₃NH][Sn(SPh)3]; TEA; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane; acetonitrile;
DOI:10.1021/jm0511334