Technology Process of Benzoic acid, 4-(2E)-2-butenyl-, methyl ester
There total 6 articles about Benzoic acid, 4-(2E)-2-butenyl-, methyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine; nickel(II) iodide; 4-chloro-2-(4,5-dihydro-1H-imidazol-2-yl)pyridine; tetrabutylammomium bromide; magnesium chloride; zinc;
In
N,N-dimethyl acetamide;
at 60 ℃;
for 12h;
regioselective reaction;
Schlenk technique;
Inert atmosphere;
DOI:10.1039/c3ob40232k
- Guidance literature:
-
With
aluminum (III) chloride; [1,1'-bis(diphenylphosphino)ferrocene]nickel(II) chloride; 3,4,7,8-Tetramethyl-o-phenanthrolin;
In
N,N-dimethyl acetamide;
at 20 - 35 ℃;
Overall yield = 62 %;
DOI:10.1039/c7sc03140h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrahydrofuran; diethyl ether / 4 h / 20 °C
2.1: magnesium; iodine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
2.2: 0.17 h / Reflux
3.1: sulfuric acid / 16 h / Reflux
4.1: cobalt(II) aceylacetonate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether / N,N-dimethyl-formamide / 16 h / 25 °C / Irradiation
With
sulfuric acid; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; iodine; potassium carbonate; cobalt(II) aceylacetonate; magnesium; bis[2-(diphenylphosphino)phenyl] ether;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1002/anie.201900849
