1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-

Base Information

Chemical Name:1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-
CAS No.:161970-92-9
Molecular Formula:C21H18N2
Molecular Weight:298.38100
Hs Code.:
DSSTox Substance ID:DTXSID30448193
Nikkaji Number:J238.366G
Wikidata:Q82267160
Mol file:161970-92-9.mol

Synonyms:1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-;161970-92-9;(4R,5R)-Isoamarine;DTXSID30448193

Suppliers and Price of 1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-

Chemical Property:

PSA：24.39000
LogP:4.28340
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:298.146998583
Heavy Atom Count:23
Complexity:398

Purity/Quality:: 95-3004%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2C(N=C(N2)C3=CC=CC=C3)C4=CC=CC=C4
Isomeric SMILES:C1=CC=C(C=C1)[C@@H]2[C@H](N=C(N2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-

There total 6 articles about 1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl-, (4R,5R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

: 5333-86-8
ethyl benzimidate hydrochloride

: 161970-92-9
(+)-(4R,5R)-2,4,5-triphenyl-trans-4,5-dihydroimidazole

Guidance literature:: In ethanol; r.t., 1 h then reflux, 4 h;
DOI:10.1055/s-1995-3864

Reference yield: 92.0%

: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

: 100-52-7
benzaldehyde

: 161970-92-9
(+)-(4R,5R)-2,4,5-triphenyl-trans-4,5-dihydroimidazole

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.tetlet.2005.02.025

Reference yield: 50.0%

: 591-50-4
iodobenzene

: 119072-55-8,7188-38-7
tert-butylisonitrile

: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

: 161970-92-9
(+)-(4R,5R)-2,4,5-triphenyl-trans-4,5-dihydroimidazole

Guidance literature:: With 1,3-bis-(diphenylphosphino)propane; caesium carbonate; palladium dichloride; In toluene; for 16h; Inert atmosphere; Reflux;
DOI:10.1021/jo400252n