1,2,3,4-Tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline

Base Information

Chemical Name:1,2,3,4-Tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline
CAS No.:165615-46-3
Molecular Formula:C16H13F3N2O2
Molecular Weight:322.287
Hs Code.:
DSSTox Substance ID:DTXSID50383875

Synonyms:165615-46-3;1,2,3,4-tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline;2-(2-Nitro-4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline;SCHEMBL3484761;DTXSID50383875

Suppliers and Price of 1,2,3,4-Tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:322.09291215
Heavy Atom Count:23
Complexity:438

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC2=CC=CC=C21)C3=C(C=C(C=C3)C(F)(F)F)[N+](=O)[O-]

Technology Process of 1,2,3,4-Tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline

There total 1 articles about 1,2,3,4-Tetrahydro-2-[2-nitro-4-(trifluoromethyl)phenyl]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene

: 165615-46-3
2-(2-nitro-4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3.5h;

Reference yield: 71.4%

: 165615-46-3
2-(2-nitro-4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline

: 175134-94-8
2-(3,4-dihydroisoquinolin-2(1H)-yl)-5-(trifluoromethyl)aniline

Guidance literature:: 2-(2-nitro-4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline; With hydrogenchloride; tin(ll) chloride; In methanol; at 0 - 20 ℃; for 18h;

With water; sodium hydrogencarbonate; In methanol;