Benzoyl azide, 4-fluoro-

Base Information

• Chemical Name: Benzoyl azide, 4-fluoro-
• CAS No.: 16664-09-8
• Molecular Formula: C7H4FN3O
• Molecular Weight: 165.127
• Mol file: 16664-09-8.mol

Synonyms:

Chemical Property of Benzoyl azide, 4-fluoro-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoyl azide, 4-fluoro-

There total 11 articles about Benzoyl azide, 4-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-Fluorobenzoic acid (456-22-4) → 4-fluorobenzoyl azide (16664-09-8)

Guidance literature:

With sodium azide; N-halosuccinimide; triphenylphosphine; In acetone; at -30 - 20 ℃; for 0.5h;

Reference yield: 90.0%

4-fluorobenzoic anhydride (25569-77-1) → 4-fluorobenzoyl azide (16664-09-8)

Guidance literature:

With sodium azide; In acetonitrile; for 0.666667h;

DOI:10.2174/1570178614666170329153759

Reference yield: 86.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-fluoro-1-iodobenzene (352-34-1) → 4-fluorobenzoyl azide (16664-09-8)

Guidance literature:

With sodium azide; C₃₉H₃₂Cl₂OP₂Pd*CH₂Cl₂; potassium carbonate; In tetrahydrofuran; hexane; water; at 20 ℃; under 760.051 Torr; Reagent/catalyst;

DOI:10.1021/om401126m

upstream raw materials:

α,α-Dibromo-4'-fluoroacetophenone

4-fluorobenzoyl chloride

4-Fluorobenzoic acid

4-fluoro-1-iodobenzene

Downstream raw materials:

para-fluorophenyl isocyanate

4-fluoro-N-(triphenyl-λ5-phosphanylidene)benzamide

p-fluorobenzamide

ethyl (E)-3-(2-cyano-5-fluorophenyl)prop-2-enoate