3-Benzyl-3-azabicyclo[3.2.1]octan-8-amine

Base Information

Chemical Name:3-Benzyl-3-azabicyclo[3.2.1]octan-8-amine
CAS No.:166973-12-2
Molecular Formula:C14H20N2
Molecular Weight:216.32200
Hs Code.:
DSSTox Substance ID:DTXSID401234907
Mol file:166973-12-2.mol

Synonyms:3-benzyl-3-azabicyclo[3.2.1]octan-8-amine;166973-12-2;SCHEMBL2844736;SCHEMBL10663383;DTXSID401234907;AT25067;EN300-64078;3-benzyl-3-aza-bicyclo[3.2.1]oct-8-ylamine;3-(Phenylmethyl)-3-azabicyclo[3.2.1]octan-8-amine

Suppliers and Price of 3-Benzyl-3-azabicyclo[3.2.1]octan-8-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Benzyl-3-azabicyclo[3.2.1]octan-8-amine

Chemical Property:

PSA：29.26000
LogP:2.49390
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:216.162648646
Heavy Atom Count:16
Complexity:221

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2CN(CC1C2N)CC3=CC=CC=C3

Technology Process of 3-Benzyl-3-azabicyclo[3.2.1]octan-8-amine

There total 2 articles about 3-Benzyl-3-azabicyclo[3.2.1]octan-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 847795-96-4
3-benzyl-N-hydroxy-3-azabicyclo[3.2.1]octan-8-imine

: 166973-12-2
3-benzyl-3-azabicyclo[3.2.1]octan-8-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -20 - 20 ℃; for 2 - 4h; Heating / reflux;

Reference yield:

: 83507-33-9
3-benzyl-3-aza-bicyclo[3.2.1]octan-8-one

: 166973-12-2
3-benzyl-3-azabicyclo[3.2.1]octan-8-amine

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol / 20 h / 15 - 50 °C / Inert atmosphere; Large scale

2: hydrogen / ethanol / 15 - 30 °C / 1500.15 - 3750.38 Torr / Large scale

With hydroxylamine hydrochloride; hydrogen; sodium acetate; In ethanol;

Reference yield:

: 166973-12-2
3-benzyl-3-azabicyclo[3.2.1]octan-8-amine

: 659736-79-5
2-cyclopentyl-2-hydroxy-2-(4-methylphenyl)acetic acid

: (endo)-N-(3-benzyl-3-azabicyclo[3.2.1]oct-8-yl)-2-cyclopentyl-2-hydroxy-2-(4-methylphenyl)acetamide

: (exo)-N-(3-benzyl-3-azabicyclo[3.2.1]oct-8-yl)-2-cyclopentyl-2-hydroxy-2-(4-methylphenyl)acetamide

Guidance literature:: 3-benzyl-3-azabicyclo[3.2.1]octan-8-amine; 2-cyclopentyl-2-hydroxy-2-(4-methylphenyl)acetic acid; With 4-methyl-morpholine; benzotriazol-1-ol; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃;