N-Cbz-guanidine

Base Information

Chemical Name:N-Cbz-guanidine
CAS No.:16706-54-0
Molecular Formula:C9H11N3O2
Molecular Weight:193.205
Hs Code.:
Mol file:16706-54-0.mol

Synonyms:N-Cbz-guanidine;16706-54-0;Benzyl N-(diaminomethylidene)carbamate;N-benzyloxycarbonylguanidine;N-carbobenzyloxyguanidine;N-carbobenzyloxy-guanidine;N-benzyloxycarbonyl guanidine;SCHEMBL1763734;FZOCFRPFPKJHHP-UHFFFAOYSA-N;MFCD09908206;BENZYL N-CARBAMIMIDOYLCARBAMATE;AKOS006313666;AS-11263;Phenylmethyl N-(aminoiminomethyl)carbamate;CS-0209170;C93432

Suppliers and Price of N-Cbz-guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 20 raw suppliers

Chemical Property of N-Cbz-guanidine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:193.085126602
Heavy Atom Count:14
Complexity:218

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)N=C(N)N

Technology Process of N-Cbz-guanidine

There total 2 articles about N-Cbz-guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 50-01-1
guanidine hydrochloride

: 501-53-1,94274-21-2
benzyl chloroformate

: 16706-54-0
N-Cbz-guanidine

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; for 10h;
DOI:10.1002/ejoc.200700756

Reference yield: 88.0%

: 123-91-1,28347-88-8,28347-91-3,39449-24-6,54841-74-6
1,4-dioxane

: 50-01-1
guanidine hydrochloride

: 501-53-1,94274-21-2
benzyl chloroformate

: 16706-54-0
N-Cbz-guanidine

Guidance literature:: With sodium hydroxide; In water;

Reference yield: 100.0%

: 1204331-18-9
4-(4-carboxy-2-methanesulfonyl-phenyl)piperidine-1-carboxylic acid tert-butyl ester

: 16706-54-0
N-Cbz-guanidine

: 1204331-19-0
4-{2-methanesulfonyl-4-[N-(carbobenzyloxy)guanidinocarbonyl]phenyl}piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 4-(4-carboxy-2-methanesulfonyl-phenyl)piperidine-1-carboxylic acid tert-butyl ester; With 2-chloro-1-methyl-pyridinium iodide; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 0.5h;

N-Cbz-guanidine; With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃;
DOI:10.1021/jm300601d