4-tert-Butyl-3,6-dichloropyridazine

Base Information

• Chemical Name: 4-tert-Butyl-3,6-dichloropyridazine
• CAS No.: 22808-29-3
• Molecular Formula: C8H10 Cl2 N2
• Molecular Weight: 205.0844
• Hs Code.: 2933990090
• European Community (EC) Number: 855-644-2
• DSSTox Substance ID: DTXSID40945486
• Nikkaji Number: J1.610.391H
• Wikidata: Q82922844
• Mol file: 22808-29-3.mol

Synonyms:4-tert-Butyl-3,6-dichloropyridazine;22808-29-3;4-(tert-Butyl)-3,6-dichloropyridazine;3,6-Dichloro-4-(1,1-dimethylethyl)pyridazine;3,6-Dichloro-4-tert-butylpyridazine;Pyridazine, 4-tert-butyl-3,6-dichloro-;Pyridazine, 3,6-dichloro-4-(1,1-dimethylethyl)-;MFCD01938756;4-tert-butyl-3,6-dichloro-pyridazine;Pyridazine,3,6-dichloro-4-(1,1-dimethylethyl)-;SCHEMBL249075;DTXSID40945486;3,6-dichloro-4-t-butylpyridazine;4-t-butyl-3,6-dichloropyridazine;BCP31976;AKOS015837947;CS-W002869;GS-4178;PB21793;SY022556;LS-129416;AM20090230;FT-0649478;EN300-633524;J-516003;Z1269241627

Chemical Property of 4-tert-Butyl-3,6-dichloropyridazine

Chemical Property:

• Vapor Pressure: 0.00241mmHg at 25°C
• Melting Point: 37-40 °C
• Refractive Index: 1.52
• Boiling Point: 297.3°Cat760mmHg
• PKA: -0.40±0.10(Predicted)
• Flash Point: 161.7°C
• PSA: 25.78000
• Density: 1.231g/cm³
• LogP: 3.08090
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: Chloroform, Dichloromethane
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 204.0221037
• Heavy Atom Count: 12
• Complexity: 156

Purity/Quality:

97% ^*data from raw suppliers

4-tert-Butyl-3,6-dichloropyridazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1=CC(=NN=C1Cl)Cl

Technology Process of 4-tert-Butyl-3,6-dichloropyridazine

There total 4 articles about 4-tert-Butyl-3,6-dichloropyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3,6-dichlorpyridazine (141-30-0) + Trimethylacetic acid (75-98-9) → 3,6-dichloro-4-(1,1-dimethylethyl)pyridazine (22808-29-3)

Guidance literature:

With ammonium peroxydisulfate; silver nitrate; trifluoroacetic acid; In water; at 55 - 75 ℃; for 1h;

Reference yield:

3,6-dichlorpyridazine (141-30-0) + ammonium persulfate → 3,6-dichloro-4-(1,1-dimethylethyl)pyridazine (22808-29-3)

Guidance literature:

With sodium hydroxide; sulfuric acid; silver nitrate; Trimethylacetic acid; In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water;

Reference yield:

3,6-dichlorpyridazine (141-30-0) + ammonium persulfate + sulfuric acid (7664-93-9) + Trimethylacetic acid (75-98-9) → 3,6-dichloro-4-(1,1-dimethylethyl)pyridazine (22808-29-3)

Guidance literature:

With silver nitrate; In hexane; water;

upstream raw materials:

3,6-dichlorpyridazine

Trimethylacetic acid

sulfuric acid

Downstream raw materials:

3,6-dichloro-4-(2-chloro-1,1-dimethylethyl)pyridazine

3,6-dichloro-4-<2-chloro-1-(chloromethyl)-1-methylethyl>pyridazine

3,6-dichloro-4-(2,2-dichloro-1,1-dimethylethyl)pyridazine

3,6-dichloro-4-<2-chloro-1,1-bis(chloromethyl)ethyl>pyridazine