ethyl 4-(3-methoxyphenylthio)-3-oxobutanoate

Base Information

Chemical Name:ethyl 4-(3-methoxyphenylthio)-3-oxobutanoate
CAS No.:16768-98-2
Molecular Formula:C13H16O4S
Molecular Weight:268.334
Hs Code.:
Mol file:16768-98-2.mol

Synonyms:Butanoic acid,4-[(3-methoxyphenyl)thio]-3-oxo-,ethyl ester;4-(3-methoxy-phenylsulfanyl)-3-oxo-butyric acid ethyl ester;4-(3-Methoxy-phenylmercapto)-3-oxo-buttersaeure-ethylester;

Suppliers and Price of ethyl 4-(3-methoxyphenylthio)-3-oxobutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of ethyl 4-(3-methoxyphenylthio)-3-oxobutanoate

Chemical Property:

PSA：77.90000
LogP:2.30960

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 4-(3-methoxyphenylthio)-3-oxobutanoate

There total 2 articles about ethyl 4-(3-methoxyphenylthio)-3-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 638-07-3
ethyl (2-chloroaceto)acetate

: 15570-12-4
3-methoxybenzenethiol

: 16768-98-2
3-methoxybenzenethiol

Guidance literature:: With potassium carbonate; In acetonitrile; at 0 - 20 ℃; for 2h;

Reference yield:

: 16768-98-2
3-methoxybenzenethiol

Guidance literature:: 3-Methoxy-thiophenol, Py., 4-Chlor-3-oxo-buttersaeure-ethylester, 25-30grad, 15 Min.;

Reference yield:

: 16768-98-2
3-methoxybenzenethiol

: 886059-76-3
5-hydroxy-2-(3-methoxy-benzenesulfonylmethyl)-1-methyl-1H-indole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 18 h / 45 °C

2: 1,2-dichloro-ethane / 8 h / Heating

3: hydrogen peroxide / sodium tungstate dihydrate / methanol; CHCl₃ / 1.5 h / 20 °C

With dihydrogen peroxide; sodium tungstate; In methanol; chloroform; 1,2-dichloro-ethane; 2: Nenitsescu condensation;
DOI:10.1016/j.bmc.2005.11.033