1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone

Base Information

• Chemical Name: 1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone
• CAS No.: 23428-77-5
• Molecular Formula: C16H16 O3
• Molecular Weight: 256.301
• Hs Code.: 2914509090
• European Community (EC) Number: 683-865-2
• NSC Number: 204990
• DSSTox Substance ID: DTXSID80308571
• Wikidata: Q82056516
• ChEMBL ID: CHEMBL2142452
• Mol file: 23428-77-5.mol

Synonyms:1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone;23428-77-5;1-(4-methoxy-3-phenylmethoxyphenyl)ethanone;MLS003107196;Ethanone, 1-[4-methoxy-3-(phenylmethoxy)phenyl]-;NSC204990;SCHEMBL9236564;CHEMBL2142452;DTXSID80308571;YAA42877;MFCD00183289;AKOS016013784;DS-5579;NSC-204990;SMR001822072;CS-0155119;1-(3-(benzyloxy)-4-methoxyphenyl)ethan-1-one;C74208;A912872;1-(3-BENZYLOXY-4-METHOXY-PHENYL)-ETHANONE

Chemical Property of 1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone

Chemical Property:

• PSA: 35.53000
• LogP: 3.47680
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 284

Purity/Quality:

97% ^*data from raw suppliers

1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C1=CC(=C(C=C1)OC)OCC2=CC=CC=C2

Technology Process of 1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone

There total 10 articles about 1-(3-(Benzyloxy)-4-methoxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-hydroxy-4-methoxyacetophenone (6100-74-9) + benzyl bromide (100-39-0) → 1‐(3‐(benzyloxy)‐4‐methoxyphenyl)ethanone (23428-77-5)

Guidance literature:

3-hydroxy-4-methoxyacetophenone; With potassium carbonate; In acetone; at 20 ℃; for 0.5h;

benzyl bromide; In acetone; for 16h; Reflux;

Reference yield: 92.5%

isovanillin (621-59-0) + benzyl chloride (100-44-7) → 1‐(3‐(benzyloxy)‐4‐methoxyphenyl)ethanone (23428-77-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 48h; Ambient temperature;

DOI:10.1016/S0040-4020(01)80559-7

Reference yield: 88.0%

1-(3-benzyloxy-4-methoxyphenyl)ethanol (154490-49-0) → 1‐(3‐(benzyloxy)‐4‐methoxyphenyl)ethanone (23428-77-5)

Guidance literature:

With potassium chromate; In acetone; at 10 ℃; for 0.75h;

DOI:10.1016/S0040-4020(01)80559-7

upstream raw materials:

3-hydroxy-4-methoxyacetophenone

benzyl chloride

benzyl bromide

isovanillin

Downstream raw materials:

ethyl 2-(3-benzyloxy-4-methoxybenzoyl) acetate

4-[(3-benzyloxy-4-methoxy-phenyl)-thioacetyl]-morpholine

3'-benzyloxy-3,4,4'-trimethoxy-chalcone

(E)-1-(3-Benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propenone