N-(benzylcarbamoyl)benzamide

Base Information

• Chemical Name: N-(benzylcarbamoyl)benzamide
• CAS No.: 17013-30-8
• Molecular Formula: C15H14N2O2
• Molecular Weight: 254.288
• DSSTox Substance ID: DTXSID60349785
• Nikkaji Number: J2.119.117E
• Wikidata: Q82125251
• ChEMBL ID: CHEMBL1430881
• Mol file: 17013-30-8.mol

Synonyms:N-(benzylcarbamoyl)benzamide;MLS000078584;N-benzoyl-N'-benzylurea;17013-30-8;SCHEMBL5013790;CHEMBL1430881;DTXSID60349785;HMS2289D08;STL336546;AKOS022136560;SMR000041870

Chemical Property of N-(benzylcarbamoyl)benzamide

Chemical Property:

• PSA: 65.18000
• LogP: 3.10540
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 254.105527694
• Heavy Atom Count: 19
• Complexity: 305

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNC(=O)NC(=O)C2=CC=CC=C2

Technology Process of N-(benzylcarbamoyl)benzamide

There total 21 articles about N-(benzylcarbamoyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-Benzoyl-3-benzyl-2-methyl-isourea (116751-89-4) → N-Benzoyl-N'-benzyl-harnstoff (17013-30-8)

Guidance literature:

With hydrogenchloride; In ethanol; for 0.166667h; Heating;

Reference yield: 85.7%

C21H16N2O2 (112776-07-5) + benzylamine (100-46-9) → Benzophenone imine (1013-88-3) + N-Benzoyl-N'-benzyl-harnstoff (17013-30-8)

Guidance literature:

Product distribution;

DOI:10.1002/ardp.19873200912

Reference yield: 80.0%

carbon monoxide (201230-82-2) + benzoyl azide (582-61-6) + benzylamine (100-46-9) → N-Benzoyl-N'-benzyl-harnstoff (17013-30-8)

Guidance literature:

With 1,10-Phenanthroline; palladium diacetate; In tetrahydrofuran; at 20 ℃; for 12h; under 15 Torr; Schlenk technique;

DOI:10.1021/acs.joc.9b01048

upstream raw materials:

(Z)-1-benzoyl-3-benzyl-2-ethylisourea

benzylamine

benzoyl isocyanate

2,6-diphenyl-[1,3,5]oxadiazin-4-one