4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione

Base Information

Chemical Name:4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione
CAS No.:170570-77-1
Molecular Formula:C11H9F3O3
Molecular Weight:246.186
Hs Code.:2914700090
European Community (EC) Number:690-681-6
Mol file:170570-77-1.mol

Synonyms:4,4-difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione;170570-77-1;SCHEMBL5685418;AMY31396;AKOS005878651;s11435;CS-0336881;A907555;A1-08734;4,4-difluoro-1-(3-fluoro-4-methoxyphenyl)-butane-1, 3-dione;4,4-difluoro-1-(3-fluoro-4-methoxyphenyl)-butane-1,3-dione;4,4-difluoro-1-(3-fluoro-4-methoxyphenyl)-butane-1.3-dione

Suppliers and Price of 4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95%
10g
$ 1650.00

Matrix Scientific
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95%
5g
$ 1156.00

Crysdot
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95+%
250mg
$ 340.00

Crysdot
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95+%
1g
$ 850.00

Chemenu
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95%
1g
$ 795.00

Arctom
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 98%
1g
$ 548.00

A1 Biochem Labs
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95%
10 g
$ 1000.00

A1 Biochem Labs
4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95%
5 g
$ 700.00

Total 11 raw suppliers

Chemical Property of 4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione

Chemical Property:

Boiling Point:350.0±37.0 °C(Predicted)
PKA:6.57±0.25(Predicted)
PSA：43.37000
Density:1.291±0.06 g/cm3(Predicted)
LogP:2.24130
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:246.05037863
Heavy Atom Count:17
Complexity:294

Purity/Quality:

97% ^*data from raw suppliers

4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(=O)CC(=O)C(F)F)F

Technology Process of 4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione

There total 2 articles about 4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)butane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 454-31-9
ethyl difluoroacetate

: 455-91-4
1-(3-fluoro-4-methoxyphenyl)ethanone

: 170570-77-1
4,4-difluoro-1-(3-fluoro-4-methoxyohenyl)-butane-1,3-dione

Guidance literature:: With hydrogenchloride; sodium methylate; In tert-butyl methyl ether;

Reference yield:

: 321-28-8
1-fluoro-2-methoxybenzene

: 170570-77-1
4,4-difluoro-1-(3-fluoro-4-methoxyohenyl)-butane-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / dichloromethane / 0.17 h / 5 - 10 °C / Cooling with ice

1.2: 1 h / 5 °C

2.1: sodium methylate / dichloromethane / 48 h

With aluminum (III) chloride; sodium methylate; In dichloromethane;