tert-Butyl Thiazol-2-ylcarbamate

Base Information

Chemical Name:tert-Butyl Thiazol-2-ylcarbamate
CAS No.:170961-15-6
Molecular Formula:C8H12N2O2S
Molecular Weight:200.261
Hs Code.:2934100090
European Community (EC) Number:693-836-6
DSSTox Substance ID:DTXSID70474491
Wikidata:Q82304534
Mol file:170961-15-6.mol

Synonyms:tert-Butyl Thiazol-2-ylcarbamate;170961-15-6;Tert-butyl N-(1,3-thiazol-2-yl)carbamate;N-Boc-2-Aminothiazole;Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI);MFCD09038327;2-(BOC-AMINO)THIAZOLE;THIAZOL-2-YL-CARBAMIC ACID TERT-BUTYL ESTER;N-Boc-2-thiazolamine;SCHEMBL14720;N-Boc-2-aminothiazole, 95%;tert-ButylThiazol-2-ylcarbamate;DTXSID70474491;NCJXQSNROJRSSL-UHFFFAOYSA-N;2-tert-butyloxycarbonylaminothiazole;AMY12048;VGA96115;AR2546;AKOS000279453;Tert-butyl 1,3-thiazol-2-ylcarbamate;AB49540;CS-W015607;SS-4334;SY110260;Thiazol-2-ylcarbamic acid tert-butyl ester;2-(TERT-BUTOXYCARBONYLAMINO)THIAZOLE;FT-0697815;EN300-196143;A811274;J-524820;tert-buttert-Butyl thiazol-2-ylcarbamateyl N-thiazol-2-ylcarbamate

Suppliers and Price of tert-Butyl Thiazol-2-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-ButylN-(1,3-Thiazol-2-yl)carbamate
500mg
$ 90.00

TRC
tert-ButylN-(1,3-Thiazol-2-yl)carbamate
50mg
$ 45.00

SynChem
TERT-BUTYL THIAZOL-2-YLCARBAMATE 95%
5 g
$ 270.00

Sigma-Aldrich
N-Boc-2-aminothiazole 95%
1g
$ 60.10

Oakwood
tert-ButylThiazol-2-ylcarbamate 95%
1g
$ 13.00

Matrix Scientific
tert-Butyl N-(1,3-thiazol-2-yl)carbamate >95%
1g
$ 228.00

Matrix Scientific
tert-Butyl N-(1,3-thiazol-2-yl)carbamate >95%
500mg
$ 181.00

Crysdot
tert-Butylthiazol-2-ylcarbamate 95%
25g
$ 175.00

ChemScene
tert-Butylthiazol-2-ylcarbamate 99.53%
100g
$ 341.00

ChemScene
tert-Butylthiazol-2-ylcarbamate 99.53%
5g
$ 41.00

Total 28 raw suppliers

Chemical Property of tert-Butyl Thiazol-2-ylcarbamate

Chemical Property:

Melting Point:180-185℃
PKA:5.25±0.70(Predicted)
PSA：79.46000
Density:1.242±0.06 g/cm3(Predicted)
LogP:2.56310
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:200.06194880
Heavy Atom Count:13
Complexity:191

Purity/Quality:

97% ^*data from raw suppliers

tert-ButylN-(1,3-Thiazol-2-yl)carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=NC=CS1

Technology Process of tert-Butyl Thiazol-2-ylcarbamate

There total 6 articles about tert-Butyl Thiazol-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 96-50-4
2-thiazolylamine

: 24424-99-5
di-tert-butyl dicarbonate

: 170961-15-6
tert-butyl 1,3-thiazole-2-yl-carbamate

Guidance literature:: With pyridine;
DOI:10.1021/ol026609h

Reference yield: 90.0%

: 96-50-4
2-thiazolylamine

: 1538-75-6
2,2-dimethylpropanoic anhydride

: 170961-15-6
tert-butyl 1,3-thiazole-2-yl-carbamate

Guidance literature:: With zinc(II) chloride; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 67.0%

: 288-47-1
1,3-thiazole

: 73210-14-7
N-chloro-N-sodio-tert-butylcarbamate

: 170961-15-6
tert-butyl 1,3-thiazole-2-yl-carbamate

Guidance literature:: With [Cu(1,3-di-iso-propylimidazolin-2-ylidene)(Cl)]; sodium t-butanolate; In tetrahydrofuran; at 60 ℃; for 12h; Inert atmosphere;
DOI:10.1021/jacs.6b07486