Eglu

Base Information

Chemical Name:Eglu
CAS No.:170984-72-2
Molecular Formula:C7H13NO4
Molecular Weight:175.18200
Hs Code.:
DSSTox Substance ID:DTXSID50415504
Nikkaji Number:J796.631H
Wikipedia:EGLU
Wikidata:Q5323047
Pharos Ligand ID:2XBBYAH6VMS2
ChEMBL ID:CHEMBL1450466
Mol file:170984-72-2.mol

Synonyms:EGLU;170984-72-2;(2S)-2-amino-2-ethylpentanedioic acid;(s)-alpha-ethylglutamate;(2s)-alpha-ethylglutamic acid;(2S)-alpha-EGLU;Tocris-0971;2-Ethyl-L-glutamic acid;D01WKR;(2S)-?-Ethylglutamic acid;SCHEMBL179812;(2S)--EGLU;GTPL1400;CHEMBL1450466;DTXSID50415504;PDSP1_000045;AKOS006275556;NCGC00024911-01;NCGC00024911-02;HY-101332;CS-0021171;J-010677;Q5323047

Suppliers and Price of Eglu

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
EGLU
1mg
$ 305.00

Usbiological
EGLU
10mg
$ 423.00

TRC
EGLU
50mg
$ 1320.00

ApexBio Technology
(S)-2-amino-2-ethylpentanedioic acid
10mg
$ 330.00

American Custom Chemicals Corporation
EGLU 95.00%
50MG
$ 1170.31

American Custom Chemicals Corporation
EGLU 95.00%
10MG
$ 697.34

American Custom Chemicals Corporation
EGLU 95.00%
1MG
$ 144.90

Total 7 raw suppliers

Chemical Property of Eglu

Chemical Property:

Boiling Point:338.5±32.0 °C(Predicted)
PKA:2.10±0.10(Predicted)
PSA：100.62000
Density:1.278±0.06 g/cm3(Predicted)
LogP:0.74360
Storage Temp.:Store at RT
XLogP3:-2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:175.08445790
Heavy Atom Count:12
Complexity:192

Purity/Quality:

95% ^*data from raw suppliers

EGLU ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CCC(=O)O)(C(=O)O)N
Isomeric SMILES:CC[C@](CCC(=O)O)(C(=O)O)N
Uses EGLU is a group II mGluR antagonist. It can also be used for acupuncture inhibition of methamphetamine-?induced behaviors, dopamine release and hyperthermia in the nucleus accumbens.

Technology Process of Eglu

There total 6 articles about Eglu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-2-Ethyl-5-oxo-pyrrolidine-2-carboxylic acid

: 170984-72-2
(2S)-α-ethylglutamic acid

Guidance literature:: With hydrogenchloride; water; In ethanol;
DOI:10.1016/S0040-4039(99)01121-1

Reference yield:

: 244127-82-0
(4S,8aS)-8a-ethyl-4-phenyltetrahydro-pyrrolo[2,1c][1,4]oxazine-1,6-dione

: 170984-72-2
(2S)-α-ethylglutamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / methanol / 2 h / Heating

2: lithium; liquid ammonia / ethanol; tetrahydrofuran / 0.08 h / -40 °C

3: hydrochloric acid / H₂O / Heating

With hydrogenchloride; potassium hydroxide; ammonia; lithium; In tetrahydrofuran; methanol; ethanol; water;
DOI:10.1016/j.tet.2004.07.100

Reference yield:

: (S)-2-Ethyl-1-((S)-2-hydroxy-1-phenyl-ethyl)-5-oxo-pyrrolidine-2-carboxylic acid

: 170984-72-2
(2S)-α-ethylglutamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: lithium; liquid ammonia / ethanol; tetrahydrofuran / 0.08 h / -40 °C

2: hydrochloric acid / H₂O / Heating

With hydrogenchloride; ammonia; lithium; In tetrahydrofuran; ethanol; water;
DOI:10.1016/j.tet.2004.07.100