2-(Phosphonomethyl)pentanedioic acid

Base Information Edit

Chemical Name:2-(Phosphonomethyl)pentanedioic acid
CAS No.:173039-10-6
Molecular Formula:C6H11O7P
Molecular Weight:226.12100
Hs Code.:
UNII:XH88WJG9LJ
DSSTox Substance ID:DTXSID90436036
Nikkaji Number:J731.897I
Pharos Ligand ID:ABH3SD6WZ3TG
ChEMBL ID:CHEMBL47009
Mol file:173039-10-6.mol

Synonyms:2-(phosphonomethyl)pentanedioic acid;2-PMPA cpd

Suppliers and Price of 2-(Phosphonomethyl)pentanedioic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Phosphonomethyl)pentanedioicAcid
50mg
$ 520.00

Tocris
PMPA(NAALADaseinhibitor)
10
$ 162.00

Tocris
PMPA(NAALADaseinhibitor)
50
$ 670.00

Medical Isotopes, Inc.
2-(Phosphonomethyl)pentanedioicacid 95+%
1 g
$ 4780.00

Matrix Scientific
2-(Phosphonomethyl)pentanedioic acid 95+%
1g
$ 8468.00

DC Chemicals
2-PMPA(NAALADaseinhibitor) >98%
250 mg
$ 900.00

DC Chemicals
2-PMPA(NAALADaseinhibitor) >98%
100 mg
$ 550.00

CSNpharm
2-PMPA
10mg
$ 99.00

CSNpharm
2-PMPA
5mg
$ 63.00

Crysdot
2-PMPA 95%
5mg
$ 41.00

Total 23 raw suppliers

Chemical Property of 2-(Phosphonomethyl)pentanedioic acid Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:538.79oC at 760 mmHg
PKA:2.06±0.10(Predicted)
Flash Point:279.65oC
PSA：141.94000
Density:1.658g/cm3
LogP:-0.27030
Storage Temp.:Desiccate at RT
Solubility.:Soluble to 100 mM in sterile
XLogP3:-2.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:226.02423968
Heavy Atom Count:14
Complexity:267

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(Phosphonomethyl)pentanedioicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)O)C(CP(=O)(O)O)C(=O)O
Uses 2-(Phosphonomethyl)pentanedioic Acid is a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor, the enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. A posiible target in the treatment of multiple sclerosis and Schizophrenia.

Technology Process of 2-(Phosphonomethyl)pentanedioic acid

There total 7 articles about 2-(Phosphonomethyl)pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%