1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPIPERIDINE

Base Information

Chemical Name:1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPIPERIDINE
CAS No.:173086-67-4
Molecular Formula:C16H21Cl2NO3
Molecular Weight:346.254
Hs Code.:
Mol file:173086-67-4.mol

Synonyms:3-(3,4-Dichloro-phenyl)-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester;1-tert-Butoxycarbonyl-3-(3,4-dichlorophenyl)-3-hydroxypiperidine;N-t-butoxycarbonyl-3-(3,4-dichlorophenyl)-3-hydroxy piperidine;

Suppliers and Price of 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPIPERIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPIPERIDINE

Chemical Property:

PSA：49.77000
LogP:4.14980

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPIPERIDINE

There total 6 articles about 1-BOC-3-(3,4-DICHLOROPHENYL)-3-HYDROXYPIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 173086-67-4
1,1-dimethylethyl 3-(3,4-dichlorophenyl)-3-hydroxy-1-piperidinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: CH₂Cl₂

2.1: SO₃*pyridine; Et₃N / CH₂Cl₂

3.1: n-BuLi / diethyl ether / -78 °C

3.2: diethyl ether

With n-butyllithium; pyridine-SO₃ complex; triethylamine; In diethyl ether; dichloromethane;
DOI:10.1016/S0960-894X(01)00538-8

Reference yield:

: 3032-81-3
3,5-dichloroiodobenzene

: 98977-36-7
3-oxo-piperidine-1-carboxylic acid tert-butyl ester

: 173086-67-4
1,1-dimethylethyl 3-(3,4-dichlorophenyl)-3-hydroxy-1-piperidinecarboxylate

Guidance literature:: With n-butyllithium; In diethyl ether; hexane; ethyl acetate;

Reference yield:

: 20555-91-3
3,4-dichloroiodobenzene

: 98977-36-7
3-oxo-piperidine-1-carboxylic acid tert-butyl ester

: 173086-67-4
1,1-dimethylethyl 3-(3,4-dichlorophenyl)-3-hydroxy-1-piperidinecarboxylate

Guidance literature:: 3,4-dichloroiodobenzene; With n-butyllithium; In diethyl ether; at -78 ℃;

3-oxo-piperidine-1-carboxylic acid tert-butyl ester; In diethyl ether;
DOI:10.1016/S0960-894X(01)00538-8