9-((tert-Butoxycarbonyl)amino)nonanoic acid

Base Information

Chemical Name:9-((tert-Butoxycarbonyl)amino)nonanoic acid
CAS No.:173435-78-4
Molecular Formula:C14H27NO4
Molecular Weight:273.36800
Hs Code.:2924199090
European Community (EC) Number:870-082-8
DSSTox Substance ID:DTXSID40400227
Wikidata:Q82203092
Mol file:173435-78-4.mol

Synonyms:173435-78-4;9-((tert-Butoxycarbonyl)amino)nonanoic acid;Boc-9-Anc-OH;9-(Boc-amino)nonanoic acid;BOC-9-AMINONONANOIC ACID;9-[(2-methylpropan-2-yl)oxycarbonylamino]nonanoic Acid;Nonanoic acid, 9-[[(1,1-dimethylethoxy)carbonyl]amino]-;9-tert-Butoxycarbonylamino-nonanoic acid;9-{[(tert-butoxy)carbonyl]amino}nonanoic acid;9-[(TERT-BUTOXYCARBONYL)AMINO]NONANOIC ACID;SCHEMBL2704961;DTXSID40400227;AMY16217;MFCD02092968;AKOS016002148;CS-W005828;BP-28242;DS-15068;N-t-Butyloxycarbonyl-9-aminononanoic acid;SY015237;FT-0740134;EN300-7406356;Z1505711964

Suppliers and Price of 9-((tert-Butoxycarbonyl)amino)nonanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Boc-9-aminononanoic acid
500mg
$ 355.00

ChemScene
9-((tert-Butoxycarbonyl)amino)nonanoicacid >97.0%
5g
$ 330.00

ChemScene
9-((tert-Butoxycarbonyl)amino)nonanoicacid >97.0%
1g
$ 90.00

ChemScene
9-((tert-Butoxycarbonyl)amino)nonanoicacid >97.0%
250mg
$ 50.00

Chem-Impex
Boc-9-aminononanoicacid,≥98% ≥98%
250MG
$ 52.42

Chem-Impex
Boc-9-aminononanoicacid,≥98% ≥98%
1G
$ 104.83

Chem-Impex
Boc-9-aminononanoicacid,98% 98%
5G
$ 375.20

Chemenu
9-((tert-Butoxycarbonyl)amino)nonanoicacid 97%
25g
$ 1324.00

Chemenu
9-((tert-Butoxycarbonyl)amino)nonanoicacid 97%
10g
$ 552.00

Chemenu
9-((tert-Butoxycarbonyl)amino)nonanoicacid 97%
5g
$ 307.00

Total 23 raw suppliers

Chemical Property of 9-((tert-Butoxycarbonyl)amino)nonanoic acid

Chemical Property:

Boiling Point:418.8±28.0 °C(Predicted)
PKA:4.78±0.10(Predicted)
PSA：75.63000
Density:1.025±0.06 g/cm3(Predicted)
LogP:3.71730
Storage Temp.:Store at 0°C
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:273.19400834
Heavy Atom Count:19
Complexity:271

Purity/Quality:

97% ^*data from raw suppliers

Boc-9-aminononanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCCCCCCCC(=O)O
Description 9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Technology Process of 9-((tert-Butoxycarbonyl)amino)nonanoic acid

There total 2 articles about 9-((tert-Butoxycarbonyl)amino)nonanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1120-12-3
9-aminononanoic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 173435-78-4
9-{[(tert-butoxy)carbonyl]amino}nonanoic acid

Guidance literature:: With sodium hydroxide; In water; tert-butyl alcohol; at 20 ℃; for 16h;
DOI:10.1021/ja903292v

Reference yield:

: 173435-78-4
9-{[(tert-butoxy)carbonyl]amino}nonanoic acid

Guidance literature:

Reference yield: 88.0%

: 173435-78-4
9-{[(tert-butoxy)carbonyl]amino}nonanoic acid

: 6325-93-5
p-nitrobenzenesulfonamide

: tert-butyl (9-((4-nitrophenyl)sulfonamido)-9-oxononyl)carbamate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1021/acsmedchemlett.1c00285