N,N-DIETHYL-2-METHOXY-BENZAMIDE

Base Information

• Chemical Name: N,N-DIETHYL-2-METHOXY-BENZAMIDE
• CAS No.: 51674-10-3
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.272
• Hs Code.: 2924299090
• Mol file: 51674-10-3.mol

Synonyms:o-Anisamide,N,N-diethyl- (7CI);2-Methoxy-N,N-diethylbenzamide;N,N-Diethyl-2-methoxybenzamide;NSC 405381;o-Methoxy-N,N-diethylbenzamide;benzamide, N,N-diethyl-2-methoxy-;N,N-diethyl(2-methoxyphenyl)carboxamide;

Chemical Property of N,N-DIETHYL-2-METHOXY-BENZAMIDE

Chemical Property:

• Vapor Pressure: 6.62E-05mmHg at 25°C
• Refractive Index: 1.512
• Boiling Point: 344.4 °C at 760 mmHg
• PKA: -0.81±0.70(Predicted)
• Flash Point: 162.1 °C
• PSA: 29.54000
• Density: 1.027 g/cm³
• LogP: 2.17720

Purity/Quality:

N,N-DIETHYL-2-METHOXY-BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-DIETHYL-2-METHOXY-BENZAMIDE

There total 12 articles about N,N-DIETHYL-2-METHOXY-BENZAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ N,N-diethyl-2-methoxybenzamide (51674-10-3)

Guidance literature:

With methanesulfonyl chloride;

at 20 ℃; for 0.166667h; Reagent/catalyst;

Reference yield: 96.5%

2-Methoxybenzoic acid (579-75-9) + diethylamine (109-89-7) → N,N-diethyl-2-methoxybenzamide (51674-10-3)

Guidance literature:

2-Methoxybenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at -10 - 20 ℃;

diethylamine; In dichloromethane; at 0 - 20 ℃; for 0.833333h;

DOI:10.1016/j.tet.2011.12.008

Reference yield: 95.0%

diethylamine (109-89-7) + 2-Methoxybenzoyl chloride (21615-34-9) → N,N-diethyl-2-methoxybenzamide (51674-10-3)

Guidance literature:

In dichloromethane; at 25 ℃; for 1h;

DOI:10.1002/poc.1753

upstream raw materials:

diethylamine

2-Methoxybenzoyl chloride

N,N-diethylsalicylamide

dimethyl sulfate

Downstream raw materials:

2-methoxy-6-methylseleno-N-diethylbenzamide

6-(2-acetoxyethyl)-6-<(N,N-diethylamino)carbonyl>-1-methoxy-1,4-cyclohexadiene

N,N-diethyl 2-carboxy-6-methoxybenzaldehyde

N,N-diethyl-2-methoxy-6-[2-(3,4-dimethoxyphenyl)-1-oxoethyl]benzamide