4-Methyl-N-(2-phenylethyl)aniline

Base Information

• Chemical Name: 4-Methyl-N-(2-phenylethyl)aniline
• CAS No.: 1739-02-2
• Molecular Formula: C15H17N
• Molecular Weight: 211.307
• DSSTox Substance ID: DTXSID80499493
• Nikkaji Number: J1.660.919F
• Wikidata: Q82350307
• Mol file: 1739-02-2.mol

Synonyms:1739-02-2;4-Methyl-N-(2-phenylethyl)aniline;SCHEMBL3904496;DTXSID80499493;AKOS000242803

Chemical Property of 4-Methyl-N-(2-phenylethyl)aniline

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 211.136099547
• Heavy Atom Count: 16
• Complexity: 176

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NCCC2=CC=CC=C2

Technology Process of 4-Methyl-N-(2-phenylethyl)aniline

There total 23 articles about 4-Methyl-N-(2-phenylethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + p-toluidine (106-49-0,12221-03-3) → N-(4-methylphenyl)-N-(2-phenylethyl)amine (1739-02-2)

Guidance literature:

With C₂₃H₁₉N₃Ni; In toluene; at 25 ℃; for 1.66667h; Green chemistry;

Reference yield: 92.0%

bis(4-methylphenyl)iodonium trifluoromethanesulfonate (123726-16-9) + phenethylamine (64-04-0) → N-(4-methylphenyl)-N-(2-phenylethyl)amine (1739-02-2)

Guidance literature:

bis(4-methylphenyl)iodonium trifluoromethanesulfonate; With sodium carbonate; Inert atmosphere; Sealed tube;

phenethylamine; In toluene; at 110 ℃; for 4h; regiospecific reaction; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201807001

Reference yield: 90.0%

2-phenylethanol (60-12-8) + 1-methyl-4-nitrobenzene (99-99-0) → N-(4-methylphenyl)-N-(2-phenylethyl)amine (1739-02-2)

Guidance literature:

With ruthenium trichloride; potassium carbonate; triphenylphosphine; glycerol; at 130 ℃; for 24h; Inert atmosphere;

DOI:10.1021/cs400049b

upstream raw materials:

N-(α-Trichlormethylbenzyl)-p-toluidin

2-phenylethyl p-nitrobenzenesulphonate

p-toluidine

2-phenylethyl tosylate