N-(4-nitrophenyl)hydrazinecarboxamide

Base Information

• Chemical Name: N-(4-nitrophenyl)hydrazinecarboxamide
• CAS No.: 17433-93-1
• Molecular Formula: C7H8N4O3
• Molecular Weight: 196.166
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID90499404
• Wikidata: Q82350152
• Mol file: 17433-93-1.mol

Synonyms:17433-93-1;N-(4-nitrophenyl)hydrazinecarboxamide;3-amino-1-(4-nitrophenyl)urea;1-amino-3-(4-nitrophenyl)urea;Hydrazinecarboxamide, N-(4-nitrophenyl)-;SCHEMBL7142294;DTXSID90499404;CEUOXWYHCUEFHS-UHFFFAOYSA-N;MFCD00041266;AKOS006337701;N-(4-nitro-phenyl)hydrazinecarboxamide;CS-0448402;1X-0324

Chemical Property of N-(4-nitrophenyl)hydrazinecarboxamide

Chemical Property:

• PSA: 116.46000
• LogP: 2.09090
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 196.05964013
• Heavy Atom Count: 14
• Complexity: 220

Purity/Quality:

99% ^*data from raw suppliers

3-Amino-1-(4-nitrophenyl)urea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1NC(=O)NN)[N+](=O)[O-]

Technology Process of N-(4-nitrophenyl)hydrazinecarboxamide

There total 12 articles about N-(4-nitrophenyl)hydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

p-nitrophenylurea (556-10-5) → 4-(4-nitrophenyl)semicarbazide (17433-93-1)

Guidance literature:

With hydrazine hydrate; sodium hydroxide; In ethanol; Reflux;

Reference yield: 70.3%

(4-nitrophenyl)carbamic acid phenyl ester (6465-01-6) → 4-(4-nitrophenyl)semicarbazide (17433-93-1)

Guidance literature:

With hydrazine hydrate; In toluene; Heating;

DOI:10.1016/j.bmc.2020.115891

Reference yield:

4-Nitrophenyl isocyanate (100-28-7) → 4-(4-nitrophenyl)semicarbazide (17433-93-1)

Guidance literature:

With hydrazine;

upstream raw materials:

p-nitrophenylurea

acetone-[4-(4-nitro-phenyl)-semicarbazone]

4-Nitrophenyl isocyanate

4-nitrobenzoyl azide

Downstream raw materials:

acetaldehyde-[4-(4-nitro-phenyl)-semicarbazone]

acetone-[4-(4-nitro-phenyl)-semicarbazone]

Acetophenon-p-nitrophenyl-semicarbazon

o-Hydroxybenzaldehyd-p-nitrophenyl-semicarbazon