3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester

Base Information

• Chemical Name: 3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester
• CAS No.: 408319-04-0
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• Mol file: 408319-04-0.mol

Synonyms:

Chemical Property of 3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester

There total 1 articles about 3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-bromoisobutyrate (600-00-0) + 1-(4-methoxyphenyl)ethanone (100-06-1) → 3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester (408319-04-0)

Guidance literature:

Multistep reaction; (i) Zn, Et₂O, benzene, (ii) /BRN= 742313/;

DOI:10.1039/j29680000436

Reference yield:

3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester (408319-04-0) → 2-(4-methoxyphenyl)-3-methyl-2-butene (13399-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) P₂O₅, benzene, (ii) aq. KOH, EtOH

2: (thermal decarboxylation) / 187.3 °C

With (thermal decarboxylation);

DOI:10.1039/j29680000436

Reference yield:

3-Hydroxy-2.2-dimethyl-3--buttersaeureethylester (408319-04-0) → 3-(4-methoxyphenyl)-2,2-dimethylbut-3-enoic acid (17580-45-9)

Guidance literature:

Multistep reaction; (i) P₂O₅, benzene, (ii) aq. KOH, EtOH;

DOI:10.1039/j29680000436

upstream raw materials:

ethyl 2-bromoisobutyrate

1-(4-methoxyphenyl)ethanone

Downstream raw materials:

3-(4-methoxyphenyl)-2,2-dimethylbut-3-enoic acid

2-(4-methoxyphenyl)-3-methyl-2-butene