1-Bromo-5-iodo-2,3,4-trimethoxybenzene

Base Information

Chemical Name:1-Bromo-5-iodo-2,3,4-trimethoxybenzene
CAS No.:174518-83-3
Molecular Formula:C9H10BrIO3
Molecular Weight:372.985
Hs Code.:
DSSTox Substance ID:DTXSID50569798
Nikkaji Number:J685.201G
Wikidata:Q82457026

Synonyms:1-bromo-5-iodo-2,3,4-trimethoxybenzene;174518-83-3;DTXSID50569798

Suppliers and Price of 1-Bromo-5-iodo-2,3,4-trimethoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-Bromo-5-iodo-2,3,4-trimethoxybenzene

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:371.88580
Heavy Atom Count:14
Complexity:181

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1Br)I)OC)OC

Technology Process of 1-Bromo-5-iodo-2,3,4-trimethoxybenzene

There total 1 articles about 1-Bromo-5-iodo-2,3,4-trimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 10385-36-1
2,3,4-trimethoxybromobenzene

: 174518-83-3
1-bromo-5-iodo-2,3,4-trimethoxybenzene

Guidance literature:: With iodine; mercury(II) oxide; In dichloromethane; for 72h; Ambient temperature;
DOI:10.1055/s-1995-4089

Reference yield: 57.0%

: 3485-84-5,26809-43-8
N-vinylphthalimide

: 174518-83-3
1-bromo-5-iodo-2,3,4-trimethoxybenzene

: 624746-05-0
2-[2-(5-bromo-2,3,4-trimethoxyphenyl)vinyl]isoindoline-1,3-dione

Guidance literature:: With N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; palladium diacetate; In acetonitrile; at 100 ℃;

Reference yield:

: 174518-83-3
1-bromo-5-iodo-2,3,4-trimethoxybenzene

: 624745-92-2
2-[2-(5-bromo-2,3,4-trimethoxyphenyl)ethyl]isoindoline-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / tri(o-tolyl)phosphane; (iPr)2NEt / Pd(OAc)2 / acetonitrile / 20 h / 100 °C

2: 100 percent / H₂ / [Ir(cod)(pyridine)(PCy₃)]PF₆ / CH₂Cl₂ / 760 Torr

With hydrogen; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; palladium diacetate; Crabtree's catalyst; In dichloromethane; acetonitrile; 1: Heck reaction;
DOI:10.1002/chem.200400220