10385-36-1

Usage

Uses

Used in Pharmaceutical Industry:
2,3,4-(Trimethoxy)bromobenzene 99 is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Synthesis:
In the field of organic chemistry, 2,3,4-(Trimethoxy)bromobenzene 99 serves as a valuable building block for the synthesis of more complex molecules. Its bromine atom can be replaced with other functional groups, enabling the creation of a wide range of compounds with diverse applications.
Used in Material Science:
The unique properties of 2,3,4-(Trimethoxy)bromobenzene 99 make it a potential candidate for the development of new materials with specific characteristics. It can be used in the synthesis of polymers, dyes, and other materials with tailored properties for various applications.
Used in Research and Development:
Due to its unique structure and reactivity, 2,3,4-(Trimethoxy)bromobenzene 99 is often utilized in research and development laboratories. It can be employed as a model compound to study various chemical reactions and mechanisms, contributing to the advancement of scientific knowledge in the field of organic chemistry.

InChI:InChI=1/C9H11BrO3/c1-11-7-5-4-6(10)8(12-2)9(7)13-3/h4-5H,1-3H3

Upstream product

• 634-36-6 1,2,3-trimethoxybenzene 
• 3901-07-3 3-(4-methoxy-phenyl)acrylic acid methyl ester 
• 5396-64-5 methyl (E)-3-(3,4-dimethoxyphenyl)acrylate 
• 95279-92-8 (E)-1-(2-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 447-53-0 1,2-Dihydronaphthalene 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 7789-69-7 phosphorus pentabromide 
• 109-04-6 2-bromo-pyridine 

Downstream Products

• 109236-82-0 2-(3,4,5-Trimethoxy-phenyl)-butyronitrile 
• 108103-48-6 N-butyl-3,4,5-trimethoxyaniline 
• 108103-63-5 Dicyclohexyl-(3,4,5-trimethoxy-phenyl)-amine 
• 262421-32-9 exo-6,exo-7-isopropylidenedioxy-3-(2,3,4-trimethoxyphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol 
• 53086-54-7 1-(2,3,4-Trimethoxyphenyl)-2,2,4,4-tetramethyl-3-[4-(pyridyl-2)-piperazinyl]-cyclobutanol 
• 53104-20-4 t-Butyl-2.3.4-trimethoxyphenylhydroxylamin 
• 5273-88-1 1-Allyl-2,3,4-trimethoxybenzene 
• 1616515-31-1 C₁₉H₂₀O₅ 
• 1616515-32-2 C₂₀H₂₂O₅ 
• 39240-15-8 1,2,3-trimethoxy-4-vinylbenzene 
• 1440956-74-0 1-((2,3,4-trimethoxyphenyl)sulfonyl)piperidine 

Relevant academic research and scientific papers

Aerobic oxidative bromination of arenes using an ionic liquid as both the catalyst and the solvent

A method for the bromination of alkoxy-substituted benzenes and naphthalenes was developed by using the residual oxygen in the reaction tube as the oxidant, and [Bmim]NO3 (1-butyl-3-methylimidazolium nitrate) ionic liquid as both the catalyst and the solvent. No other reagent apart from the ionic liquid and molecular bromine was used in the reactions, and basically all the bromine atoms in the bromine source were transferred to the bromination products, showing that the presented protocol is highly atom economic and practical.

Palladium-catalyzed homocoupling of aryl halides in the presence of fluoride

This report describes the fluoride-mediated homocoupling of aryl iodides and bromides catalyzed by palladium(0). This coupling protocol is tolerant of electron-donating and electron-withdrawing substitutents on the aryl halide, as well as ortho substitution. Optimum reaction conditions entail 10 mol% Pd(dba)2, 3 equiv of tetrabutyl ammonium fluoride (TBAF) in DMF at 90°C.

A convenient and selective method for the para-bromination of aromatic compounds with potassium bromide in the presence of poly(4-vinylpyridine)- supported peroxodisulfate in nonaqueous solution

A convenient and selective procedure for the para-bromination of aromatic compounds has been developed using potassium bromide in the presence of poly(4-vinylpyridine)-supported peroxodisulfate in nonaqueous solution.

Regioselective aromatic monobromination of alkyl phenyl ethers with NaClO2, NaBr, Mn(acac)3, and Montmorillonite K10 in dichloromethane

Regioselective and high-yielding nuclear monobromination of aromatic ethers can be accomplished with a combination of NaClO2, NaBr, and Mn(acac)3 catalyst in dilchloromethane under mild and neutral conditions with the aid of Montmorillonite K10.

Open versus Closed Polyaromatic Nanocavity: Enhanced Host Abilities toward Large Dyes and Pigments

Host functions of polyaromatic nanocavities were revealed by using an M2L4 molecular cage and capsule. On the basis of the previously reported M2L4 capsule with a closed polyaromatic cavity, a new M2L

Poly(4-vinylpyridinium bromochromate): An efficient reagent for bromination of aromatic compounds

A simple and efficient method for the bromination of various aromatic compounds by using poly(4-vinylpyridinium bromochromate) is reported. This method has several advantages such as good selectivity between ortho and para positions of aromatic compounds, simple workup, short reaction times, and high yields of the products.

Simple and improved regioselective brominations of aromatic compounds using N-benzyl-N,N-dimethylanilinium peroxodisulfate in the presence of potassium bromide under mild reactions conditions

A simple, efficient, and mild method for the selective bromination of some activated aromatic compounds using N-benzyl-N,N-dimethylanilinium peroxodisulfate in the presence of potassium bromide in non-aqueous solution is reported. The results obtained revealed good to excellent selectivity between the ortho and para positions of phenols and methoxyarenes.

Palladium-catalyzed cross-coupling of aryl triethylammonium bis(catechol) silicates with aryl bromides using microwave irradiation

(Chemical Equation Presented) The scope of the palladium-catalyzed cross-coupling reaction of aryl bis(catechol) silicates has been extended to include the coupling of aryl bromides by employing microwave irradiation. This new set of coupling conditions is tolerant of electron-rich and -deficient aryl bromides. In addition, a variety of substituted aryl bis(catechol) silicates have been successfully cross-coupled.

Nuclear monobromination of alkyl phenyl ethers with NaClO2, NaBr, Mn(acac)3, and moist silica gel in aprotic solvent

Nuclear monobromination of aromatic ethers can be achieved with a NaClO2/NaBr/Mn(acac)3 catalyst/silica gel system in dichloromethane in regioselective and high-yielding manner under mild conditions.

Bromination of some aromatic compounds with potassium bromide in the presence of benzyltriphenylphosphonium peroxodisulfate

A simple, efficient, and mild method for selective bromination of some activated aromatic compounds using potassium bromide in the presence of benzyltriphenylphosphonium peroxodisulfate in nonaqueous solution is reported. The results obtained revealed good to excellent selectivity between ortho and para positions of phenols and methoxyarenes. Copyright Taylor & Francis Group, LLC.