(S)-A-HYDROXY-3-THIOPHENEACETONITRILE

Base Information

Chemical Name:(S)-A-HYDROXY-3-THIOPHENEACETONITRILE
CAS No.:174754-56-4
Molecular Formula:C6H5NOS
Molecular Weight:139.17500
Hs Code.:
Mol file:174754-56-4.mol

Synonyms:(S)-A-Hydroxy-3-Thiopheneacetonitrile;

Suppliers and Price of (S)-A-HYDROXY-3-THIOPHENEACETONITRILE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of (S)-A-HYDROXY-3-THIOPHENEACETONITRILE

Chemical Property:

PSA：72.26000
LogP:1.30508

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-A-HYDROXY-3-THIOPHENEACETONITRILE

There total 2 articles about (S)-A-HYDROXY-3-THIOPHENEACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 498-62-4
3-thiophene carboxaldehyde

: 74-90-8
hydrogen cyanide

: 174754-56-4
(S)-Hydroxy-thiophen-3-yl-acetonitrile

Guidance literature:: In di-isopropyl ether; at 25 ℃; for 4h; hydroxynitrile lyase (S)-MeHNL (EC 4.1.2.37), nitrocellulose;

Reference yield:

: 498-62-4
3-thiophene carboxaldehyde

: 773837-37-9
sodium cyanide

: 174754-56-4
(S)-Hydroxy-thiophen-3-yl-acetonitrile

: 188481-44-9
(R)-(-)-2-hydroxy-2-(3-thienyl)acetonitrile

Guidance literature:: sodium cyanide; With (S)-hydroxynitrile lyase; acetic acid; In water; isopropyl alcohol; for 48h; Cooling with ice; Enzymatic reaction;

3-thiophene carboxaldehyde; In water; isopropyl alcohol; for 48h; enantioselective reaction; Cooling with ice;
DOI:10.1016/j.tetasy.2013.03.015