(4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

Base Information

Chemical Name:(4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole
CAS No.:175226-83-2
Molecular Formula:C13H17NO
Molecular Weight:203.284
Hs Code.:
DSSTox Substance ID:DTXSID00440725
Wikidata:Q82257101

Synonyms:175226-83-2;CTK0E3950;(4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole;DTXSID00440725

Suppliers and Price of (4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

Chemical Property:

Boiling Point:294.1±19.0 °C(Predicted)
PSA：21.59000
Density:1.04±0.1 g/cm3(Predicted)
LogP:2.11800
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:203.131014166
Heavy Atom Count:15
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1COC(=N1)CC2=CC=CC=C2
Isomeric SMILES:CC(C)[C@H]1COC(=N1)CC2=CC=CC=C2

Technology Process of (4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole

There total 2 articles about (4S)-2-benzyl-4-propan-2-yl-4,5-dihydro-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 103-82-2
phenylacetic acid

: 2026-48-4,473-75-6
(S)-valinol

: 175226-83-2
(4S)-2-benzyl-4-isopropyl-4,5-dihydrooxazole

Guidance literature:: phenylacetic acid; (S)-valinol; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

With sodium hydroxide; In ethanol; at 70 ℃; for 12h; Inert atmosphere;
DOI:10.1039/c9cc00557a

Reference yield: 59.0%

: 2026-48-4,473-75-6
(S)-valinol

: 5442-34-2
ethyl 2-phenylacetimidate hydrochloride

: 175226-83-2
(4S)-2-benzyl-4-isopropyl-4,5-dihydrooxazole

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1039/b506391d

Reference yield: 87.0%

: 1246011-22-2
methyl 3-((tert-butyldimethylsilyl)oxy)-2-diazopent-3-enoate

: 175226-83-2
(4S)-2-benzyl-4-isopropyl-4,5-dihydrooxazole

: C₂₅H₃₉NO₄Si

Guidance literature:: With silver hexafluoroantimonate; In chloroform; at 20 ℃; for 12h; regioselective reaction; Molecular sieve;
DOI:10.1002/anie.202101641