4-(4-AMINO-PHENYL)-THIAZOL-2-YLAMINE

Base Information

• Chemical Name: 4-(4-AMINO-PHENYL)-THIAZOL-2-YLAMINE
• CAS No.: 3673-53-8
• Molecular Formula: C9H9 N3 S
• Molecular Weight: 191.257
• Hs Code.: 2934100090
• Mol file: 3673-53-8.mol

Synonyms:Thiazole,2-amino-4-(p-aminophenyl)- (6CI,7CI,8CI); 4-(4-Aminophenyl)-2-aminothiazole;4-(4-Aminophenyl)-2-thiazolamine

Chemical Property of 4-(4-AMINO-PHENYL)-THIAZOL-2-YLAMINE

Chemical Property:

• Vapor Pressure: 3.64E-07mmHg at 25°C
• Melting Point: 177-182°C
• Boiling Point: 417.1°C at 760 mmHg
• Flash Point: 206°C
• PSA: 93.17000
• Density: 1.347g/cm³
• LogP: 3.13690
• Storage Temp.: 2-8°C

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-(4-Aminophenyl)thiazol-2-amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-(4-AMINO-PHENYL)-THIAZOL-2-YLAMINE

There total 7 articles about 4-(4-AMINO-PHENYL)-THIAZOL-2-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-(4-nitro-phenyl)-thiazol-2-ylamine (2104-09-8) + 4-Nitrophenacyl bromide (99-81-0) → 2-amino-4-(4-amino-phenyl)-thiazole (3673-53-8)

Guidance literature:

With thiourea; In DMF on palladium; pyrographite;

Reference yield: 80.0%

4-Ethynylaniline (14235-81-5) + thiourea (17356-08-0) → 2-amino-4-(4-amino-phenyl)-thiazole (3673-53-8)

Guidance literature:

With N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide; sodium alginate; In water; at 70 ℃; for 4h; Green chemistry;

DOI:10.1016/j.molstruc.2021.129900

Reference yield: 72.0%

p-aminobenzophenone (99-92-3) + thiourea (17356-08-0) → 2-amino-4-(4-amino-phenyl)-thiazole (3673-53-8)

Guidance literature:

With sodium iodine dichloride; In tetrahydrofuran; water; for 12h; Reflux;

DOI:10.1016/j.tetlet.2014.11.140

upstream raw materials:

p-aminobenzophenone

thiourea

4-(4-nitro-phenyl)-thiazol-2-ylamine

4-Nitrophenacyl bromide

Downstream raw materials:

4-(4-amino-phenyl)-5-bromo-thiazol-2-ylamine

N-4-(4-aminophenyl)-thiazol-2-yl-chloroacetamide

4-<(2-amino-4-thiazolyl)-phenylamino>-7-chloroquinoline

4-<4-(2-carbomethoxyamino-4-thiazolyl)phenylamino>-7-chloroquinoline